FlyBase Allele Report: Dmel\sog[KK101420]

General Information

Symbol

Dmel\sog^KK101420

Species

D. melanogaster

Name

FlyBase ID

FBal0231259

Feature type

allele

Associated gene

Dmel\sog

Associated Insertion(s)

Carried in Construct

P{KK101420}

Genomic Maps

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Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

in vitro construct - RNAi

(Keleman et al., 2009.8.5)

in vitro construct - regulatory fusion

(Keleman et al., 2009.8.5)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Carried in construct

P{KK101420}

Cytology

Nature of the lesion

Statement

Reference

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Product class / Tool use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

sog

Associated Sequence Features

dsRNA-KK101420

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4²²¹

(Hattori et al., 2013)

Phenotype Manifest In

abdominal dorsal multidendritic neuron ddaD | third instar larval stage, with Scer\GAL4²²¹

(Hattori et al., 2013)

abdominal dorsal multidendritic neuron ddaE | third instar larval stage, with Scer\GAL4²²¹

(Hattori et al., 2013)

dendritic tree | third instar larval stage, with Scer\GAL4²²¹

(Hattori et al., 2013)

Detailed Description

Statement

Reference

The expression of sog^KK101420 under the control of Scer\GAL4^c564 has no obvious affect on the inflammatory response to Gram-positive bacterial infection or under basal conditions, as compared to controls.

(Kumar et al., 2016)

The expression of sog^KK101420 under the control of Scer\GAL4²²¹, in combination with Dicer-2 for efficient RNAi, results in third instar larval class I abdominal dorsal multidendritic ddaD and ddaE neurons exhibiting dendrite branch misrouting, as compared to controls; expression under the control of Scer\GAL4^ppk.PG, in combination with Dicer-2 for efficient RNAi, results in no obvious dendrite morphology defects in class IV abdominal dorsal multidendritic ddaC neurons, as compared to controls.

(Hattori et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v105853

P{KK101420}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

sog^KK101420

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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