FlyBase Allele Report: Dmel\Cat[KK101528]

General Information

Symbol

Dmel\Cat^KK101528

Species

D. melanogaster

Name

FlyBase ID

FBal0231328

Feature type

allele

Associated gene

Dmel\Cat

Associated Insertion(s)

Carried in Construct

P{KK101528}

Also Known As

UAS-Catalase-RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK101528}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK101528

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | adult stage, with Scer\GAL4^elav-C155

(Wu et al., 2017)

lethal, with Scer\GAL4^Mef2.PR

(Ham et al., 2023)

Phenotype Manifest In

adult brain, with Scer\GAL4^elav-C155

(Wu et al., 2017)

embryonic/larval plasmatocyte | adult stage, with Scer\GAL4^elav-C155

(Wu et al., 2017)

Detailed Description

Statement

Reference

Expression of Cat^KK101528 under the control of Scer\GAL4^elav-C155 leads to a significant increase in recruitment of plasmatocytes to the brain, as compared to controls.

(Wu et al., 2017)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Cat^KK101528, Scer\GAL4^elav-C155 is an enhancer of abnormal neuroanatomy phenotype of Hsap\APP^{Aβ42.UAS.cBa}, Scer\GAL4^elav-C155

(Wu et al., 2017)

Phenotype Manifest In

Enhancer of

Statement

Reference

Cat^KK101528, Scer\GAL4^elav-C155 is an enhancer of adult brain phenotype of Hsap\APP^{Aβ42.UAS.cBa}, Scer\GAL4^elav-C155

(Wu et al., 2017)

Cat^KK101528, Scer\GAL4^elav-C155 is an enhancer of embryonic/larval plasmatocyte | adult stage phenotype of Hsap\APP^{Aβ42.UAS.cBa}, Scer\GAL4^elav-C155

(Wu et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Co-expression of Cat^KK101528 leads to a significant increase in recruitment of plasmatocytes to the brain in flies that express Hsap\APP^{Aβ42.Scer\UAS.cBa} under the control of Scer\GAL4^elav-C155.

(Wu et al., 2017)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v103591

P{KK101528}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Cat^KK101528

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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