FlyBase Allele Report: Dmel\dpn[KK101812]

General Information

Symbol

Dmel\dpn^KK101812

Species

D. melanogaster

Name

FlyBase ID

FBal0231493

Feature type

allele

Associated gene

Dmel\dpn

Associated Insertion(s)

Carried in Construct

P{KK101812}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK101812}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK101812

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^en-e16E

(Babaoğlan et al., 2013)

Phenotype Manifest In

wing, with Scer\GAL4^en-e16E

(Babaoğlan et al., 2013)

Detailed Description

Statement

Reference

Expression of dpn^KK101812 under the control of Scer\GAL4^Bx-MS1096 has no effect on male wing size or patterning.

Expression of dpn^KK101812 under the control of Scer\GAL4^Bx-MS1096 has no effect on female wing size or patterning.

(Schertel et al., 2015)

19% of flies expressing dpn^KK101812 under the control of Scer\GAL4^en-e16E have a single nick in the wing.

(Babaoğlan et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^wor.PA/dpn^KK101812, Scer\GAL80^ase.PN is a suppressor of partially lethal - majority die phenotype of Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, brat^GD7073

(Reichardt et al., 2018)

Scer\GAL4^wor.PA/dpn^KK101812, Scer\GAL80^ase.PN is a suppressor of neoplasia | adult stage phenotype of Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, brat^GD7073

(Reichardt et al., 2018)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^wor.PA/dpn^KK101812, Scer\GAL80^ase.PN is a suppressor of adult brain phenotype of Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, brat^GD7073

(Reichardt et al., 2018)

Additional Comments

Genetic Interactions

Statement

Reference

The co-expression of dpn^KK101812 strongly suppresses both the adult lethality and the adult brain tumor phenotype of individuals expressing brat^GD7073 under the combined control of Scer\GAL4^wor.PA, Scer\GAL80^ase.PN.

(Reichardt et al., 2018)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v106181

P{KK101812}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

dpn^KK101812

dpn^RNAi

(Bonnay et al., 2020)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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