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General Information
Symbol
Dmel\DarkKK104215
Species
D. melanogaster
Name
FlyBase ID
FBal0232822
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The expression of DarkKK104215 under the control of Scer\GAL4ap-md544 does not induce opaque or curly wings, which would be indicative of apoptosis or growth inhibition, respectively.

Expression under the control of Scer\GAL4C10 does not affect the overall wing size.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The eye defects characteristic for adult flies expressing any of the following: DroncUAS.cSa, DroncS130A.UAS.cSa and Dcp-1UAS.cKa (photoreceptor depigmentation) or Diap1dsRNA.UAS.cLa (depigmentation and size reduction) under the control of Scer\GAL4GMR.PFa or those carrying one copy of grimGMR.PC are all strongly improved by Scer\GAL4GMR.PFa-driven expression of DarkKK104215.

The small rough eyes observed in flies expressing rprScer\UAS.C under the Scer\GAL4GMR.PFa driver is only partially suppressed (the size is rescued but not the rough appearance) by co-expression of DarkKK104215, however, when DarkKK104215 is combined with Usp15-31KK101035, it leads to a complete suppression. Combination of DarkKK104215 with another transgene, Usp8KK100733 on the other hand does not strengthen the rescue.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
ArkKK104215
DarkKK104215
Name Synonyms
Secondary FlyBase IDs
    References (4)