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General Information
Symbol
Dmel\CalpAKK104532
Species
D. melanogaster
Name
FlyBase ID
FBal0233044
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

Co-expression of CalpAKK104532 results in a clear reduction in the number of aggregates observed in the eyes of flies expressing Scer\GAL4GMR.PF>Hsap\HTTQ46.ex1p.Scer\UAS.T:Avic\GFP-EGFP.

Co-expression of Scer\GAL4GMR.PF>CalpAKK104532 partially suppresses the toxicity of Hsap\HTTGMR.Q120 in the eye.

Co-expression of CalpAKK104532 leads to a significant reduction in the number of flies with black necrotic-like spots in the eye, in both males and females expressing Scer\GAL4GMR.PF>Zzzz\CAGQ48.Scer\UAS.T:Hsap\MYC,T:Zzzz\FLAG.

Co-expression of CalpAKK104532 in an Atg8aKG07569 mutant genetic background fails to reduce the number of aggregates observed in the eyes of flies expressing Scer\GAL4GMR.PF>Hsap\HTTQ46.ex1p.Scer\UAS.T:Avic\GFP-EGFP.

Co-expression of CalpAKK104532 in an Atg8aKG07569 mutant genetic background exacerbates the toxicity of Hsap\HTTGMR.Q120 expression in the eye.

Co-expression of CalpAKK104532 can protect from the toxicity of Scer\GAL4GMR.PF>Hsap\MAPTScer\UAS.cWa expression as measured by the eye area of flies.

Co-expression of CalpAKK104532 in an Atg8aKG07569 mutant genetic background fails to suppress the toxicity of Scer\GAL4GMR.PF>Hsap\MAPTScer\UAS.cWa.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
CalpAKK101294
CalpAKK104532
Name Synonyms
Secondary FlyBase IDs
    References (2)