Scer\GAL4^69B-mediated expression results in larval cuticle molting defects - mutants show characteristic double-cuticles of head skeleton and posterior spiracles in the second and third instar larvae.

Scer\GAL4^69B-mediated expression results in large epidermal lesions at wounded sites of first instar and immediate lethality.

Scer\GAL4^69B-mediated expression results in epidermal cuticle morphology defects in third instars - unusually narrowed ECM thickness and deformed chitin-matrix, and absence of lamellate chitin-scaffolds.

Scer\GAL4^69B-mediated expression results in unusually wrinkled epidermal procuticle morphology which partially affects the 'cuticle assembly zone' in second instars. In third instars, the epidermal procuticle appears degraded and its thickening is disturbed, finally causing narrowed cuticle size.

Unlike in wild type, Pseudomonas can penetrate the cuticle of Scer\GAL4^69B Idgf6^KK106193 larvae.