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General Information
Symbol
Dmel\Ufd1-likeKK108134
Species
D. melanogaster
Name
FlyBase ID
FBal0235373
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The expression of Ufd1-likeKK108134 under the control of Scer\GAL4da.G32 induces significant locomotor defects in both larvae (lower distances traveled) and adults (progressive decrease in climbing behavior in negative geotaxis assays). Larval NMJs show microtubules defects (frequently lacking Futsch staining) but apparently normal branch sizes, as compared to controls. Motor neuron axons do not show any obvious microtubule or ER defects.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
NOT Enhanced by
NOT suppressed by
Enhancer of
NOT Enhancer of
NOT Suppressor of
Other
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of Ufd1-likeKK108134 with TER94A229E.Scer\UAS under the control of Scer\GAL4GMR.PF results in lethality.

Expression of Ufd1-likeKK108134 does not reverse the suppressive effect of Der-1Scer\UAS.cLa on the rough eye and photoreceptor degeneration phenotypes seen when TER94R188Q.Scer\UAS is expressed under the control of Scer\GAL4GMR.PF.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Ufd1-likeKK108134
Name Synonyms
Secondary FlyBase IDs
    References (5)