Allele Dmel\CG4096^KK108644

General Information
Symbol	Dmel\CG4096^KK108644	Species	D. melanogaster
Name		FlyBase ID	FBal0235709
Feature type	allele	Associated gene	Dmel\CG4096

Map ( GBrowse )
Allele class
Mutagen	in vitro construct - RNAi, in vitro construct - regulatory fusion
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Keleman et al., 2009.8.5) in vitro construct - RNAi (Keleman et al., 2009.8.5)
Mutations Mapped to the Genome

Type Location Additional Notes References RNAi reagent :1..354
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS regulatory sequences drive expression of an inverted repeat. (Keleman et al., 2009.8.5)
Carried in construct	P{KK108644} (Keleman et al., 2009.8.5, Butchar et al., 2012)
Associated Sequence Features	dsRNA-KK108644
Cytology
Phenotypic Data
Phenotypic Class
	visible, with Scer\GAL4^Act5C.PU (Butchar et al., 2012)
Phenotype Manifest In
	wing, with Scer\GAL4^Act5C.PU (Butchar et al., 2012) wing vein \| ectopic, with Scer\GAL4^Act5C.PU (Butchar et al., 2012)
Detailed Description
	Statement Reference Expression of CG4096[KK108644] under the control of Scer\GAL4[Act5C.PU] results in an extra vein phenotype with an additional vin fragment above vein L2 and some vein deltas and a reduction in wing size. (Butchar et al., 2012)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement Reference CG4096^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, suppressible \| partially by spi¹/Krn²⁷ (Butchar et al., 2012) CG4096^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, suppressible \| partially by vn^L6/Krn²⁷ (Butchar et al., 2012) CG4096^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, suppressible by Ras85D^e1B (Butchar et al., 2012) CG4096^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, suppressible by spi¹/vn^L6/Krn²⁷ (Butchar et al., 2012)
NOT suppressed by
Statement Reference CG4096^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, non-suppressible by Df(2R)Egfr3 (Butchar et al., 2012) CG4096^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, non-suppressible by Krn²⁷ (Butchar et al., 2012) CG4096^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, non-suppressible by pnt^Δ88 (Butchar et al., 2012) CG4096^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, non-suppressible by spi¹ (Butchar et al., 2012) CG4096^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, non-suppressible by spi¹/vn^L6 (Butchar et al., 2012) CG4096^KK108644, Scer\GAL4^Act5C.PU has visible phenotype, non-suppressible by vn^ddd-3 (Butchar et al., 2012)
Enhancer of
Statement Reference Scer\GAL4^Act5C.PU/CG4096^KK108644 is an enhancer of visible phenotype of Egfr^E1 (Butchar et al., 2012)
Phenotype Manifest In
Suppressed by
Statement Reference CG4096^KK108644, Scer\GAL4^Act5C.PU has wing vein \| ectopic phenotype, suppressible \| partially by spi¹/Krn²⁷ (Butchar et al., 2012) CG4096^KK108644, Scer\GAL4^Act5C.PU has wing vein \| ectopic phenotype, suppressible \| partially by vn^L6/Krn²⁷ (Butchar et al., 2012) CG4096^KK108644, Scer\GAL4^Act5C.PU has wing vein \| ectopic phenotype, suppressible by Ras85D^e1B (Butchar et al., 2012) CG4096^KK108644, Scer\GAL4^Act5C.PU has wing vein \| ectopic phenotype, suppressible by spi¹/vn^L6/Krn²⁷ (Butchar et al., 2012)
NOT suppressed by
Statement Reference CG4096^KK108644, Scer\GAL4^Act5C.PU has wing vein \| ectopic phenotype, non-suppressible by Df(2R)Egfr3 (Butchar et al., 2012) CG4096^KK108644, Scer\GAL4^Act5C.PU has wing vein \| ectopic phenotype, non-suppressible by Krn²⁷ (Butchar et al., 2012) CG4096^KK108644, Scer\GAL4^Act5C.PU has wing vein \| ectopic phenotype, non-suppressible by pnt^Δ88 (Butchar et al., 2012) CG4096^KK108644, Scer\GAL4^Act5C.PU has wing vein \| ectopic phenotype, non-suppressible by spi¹ (Butchar et al., 2012) CG4096^KK108644, Scer\GAL4^Act5C.PU has wing vein \| ectopic phenotype, non-suppressible by spi¹/vn^L6 (Butchar et al., 2012) CG4096^KK108644, Scer\GAL4^Act5C.PU has wing vein \| ectopic phenotype, non-suppressible by vn^ddd-3 (Butchar et al., 2012)
Enhancer of
Statement Reference Scer\GAL4^Act5C.PU/CG4096^KK108644 is an enhancer of wing vein \| ectopic phenotype of Egfr^E1 (Butchar et al., 2012)
Additional Comments
Genetic Interactions
Statement Reference Expression of CG4096[KK108644] under the control of Scer\GAL4[Act5C.PU] enhances the extra wing vein phenotype of Egfr[E1] flies. The extra wing vein phenotype caused by expression of CG4096[KK108644] under the control of Scer\GAL4[Act5C.PU] is not suppressed if the flies also carry one of Df(2R)Egfr3, pnt[Δ88], spi[1], vn[ddd-3] or Krn[27]. The extra wing vein phenotype caused by expression of CG4096[KK108644] under the control of Scer\GAL4[Act5C.PU] is not suppressed if the flies also simultaneously carry vn[L6] and spi[1]. The extra wing vein phenotype caused by expression of CG4096[KK108644] under the control of Scer\GAL4[Act5C.PU] is significantly suppressed if the flies also carry Ras85D[e1B]. The extra wing vein phenotype caused by expression of CG4096[KK108644] under the control of Scer\GAL4[Act5C.PU] is significantly suppressed if the also simultaneously carry both spi[1] and Krn[27], or both vn[L6] and Krn[27]. The suppression is more pronounced if the flies simultaneously carry spi[1], Krn[27] and vn[L6]. (Butchar et al., 2012)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 1 )
VDRC	v108353 P{KK108644}VIE-260B
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG4096^KK108644
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Butchar et al., 2012, Genetics 191(4): 1213--1226 New negative feedback regulators of egfr signaling in Drosophila. [FBrf0219175]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510]

Allele Dmel\CG4096KK108644

Allele Dmel\CG4096^KK108644