FlyBase Allele Report: Dmel\hth[KK108831]

General Information

Symbol

Dmel\hth^KK108831

Species

D. melanogaster

Name

FlyBase ID

FBal0235855

Feature type

allele

Associated gene

Dmel\hth

Associated Insertion(s)

Carried in Construct

P{KK108831}

Also Known As

UAS-hth^RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK108831}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK108831

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^Bx-MS1096

(Schertel et al., 2015)

Phenotype Manifest In

wing, with Scer\GAL4^Bx-MS1096

(Schertel et al., 2015)

Detailed Description

Statement

Reference

Larvae expressing hth^KK108831 under the control of Scer\GAL4^Hml.Δ do not show changes in the number of lymph gland hemocytes, as compared to controls.

(Baril et al., 2017)

Expression of hth^KK108831 under the control of Scer\GAL4^Bx-MS1096 results in male flies with weak wing size and patterning defects.

Expression of hth^KK108831 under the control of Scer\GAL4^Bx-MS1096 results in female flies with weak wing size and patterning defects.

(Schertel et al., 2015)

Expression of hth^KK108831 (co-expressed with Dcr-2^Scer\UAS.cDa) under the control of Scer\GAL4^repo.PU has no detectable effect on glial cell number in the third instar larval eye disc.

(Reddy and Irvine, 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

hth^KK108831, Scer\GAL4^GMR.PFa is a suppressor | partially of abnormal cell number | larval stage phenotype of Rbf^120a, Scer\GAL4^GMR.PFa, yki^{S111A.S168A.S250A.UAS.Tag:V5}

(Rader et al., 2023)

hth^KK108831, Scer\GAL4^GMR.PFa is a suppressor | partially of increased occurrence of cell division | larval stage phenotype of Rbf^120a, Scer\GAL4^GMR.PFa, yki^{S111A.S168A.S250A.UAS.Tag:V5}

(Rader et al., 2023)

hth^KK108831/Scer\GAL4^repo.PU is a suppressor of increased cell number | third instar larval stage phenotype of Scer\GAL4^repo.PU, yki^{S168A.UAS.Tag:V5}

(Reddy and Irvine, 2011)

NOT Suppressor of

Statement

Reference

hth^KK108831, Scer\GAL4^Hml.Δ is a non-suppressor of increased cell number | third instar larval stage phenotype of Hsap\HOXA9::Hsap\NUP98^WT.UAS, Scer\GAL4^Hml.Δ

(Baril et al., 2017)

hth^KK108831/exd^GD1439, Scer\GAL4^Hml.Δ is a non-suppressor of increased cell number | third instar larval stage phenotype of Hsap\HOXA9::Hsap\NUP98^WT.UAS, Scer\GAL4^Hml.Δ

(Baril et al., 2017)

Other

Statement

Reference

Scer\GAL4^GMR.PFa, hth^KK108831, yki^{S111A.S168A.S250A.UAS.Tag:V5} has increased occurrence of cell division | larval stage phenotype

(Rader et al., 2023)

Scer\GAL4^GMR.PFa, hth^KK108831, yki^{S111A.S168A.S250A.UAS.Tag:V5} has abnormal cell number | larval stage phenotype

(Rader et al., 2023)

Phenotype Manifest In

Suppressor of

Statement

Reference

hth^KK108831, Scer\GAL4^GMR.PFa is a suppressor | partially of photoreceptor cell R8 | larval stage phenotype of Rbf^120a, Scer\GAL4^GMR.PFa, yki^{S111A.S168A.S250A.UAS.Tag:V5}

(Rader et al., 2023)

hth^KK108831, Scer\GAL4^GMR.PFa is a suppressor | partially of eye disc | larval stage phenotype of Rbf^120a, Scer\GAL4^GMR.PFa, yki^{S111A.S168A.S250A.UAS.Tag:V5}

(Rader et al., 2023)

hth^KK108831/Scer\GAL4^repo.PU is a suppressor of eye disc | third instar larval stage phenotype of Scer\GAL4^repo.PU, yki^{S168A.UAS.Tag:V5}

(Reddy and Irvine, 2011)

hth^KK108831/Scer\GAL4^repo.PU is a suppressor of larval glial cell | third instar larval stage phenotype of Scer\GAL4^repo.PU, yki^{S168A.UAS.Tag:V5}

(Reddy and Irvine, 2011)

NOT Suppressor of

Statement

Reference

hth^KK108831, Scer\GAL4^Hml.Δ is a non-suppressor of embryonic/larval lymph gland | third instar larval stage phenotype of Hsap\HOXA9::Hsap\NUP98^WT.UAS, Scer\GAL4^Hml.Δ

(Baril et al., 2017)

hth^KK108831, Scer\GAL4^Hml.Δ is a non-suppressor of embryonic/larval hemocyte | third instar larval stage phenotype of Hsap\HOXA9::Hsap\NUP98^WT.UAS, Scer\GAL4^Hml.Δ

(Baril et al., 2017)

hth^KK108831/exd^GD1439, Scer\GAL4^Hml.Δ is a non-suppressor of embryonic/larval lymph gland | third instar larval stage phenotype of Hsap\HOXA9::Hsap\NUP98^WT.UAS, Scer\GAL4^Hml.Δ

(Baril et al., 2017)

hth^KK108831/exd^GD1439, Scer\GAL4^Hml.Δ is a non-suppressor of embryonic/larval hemocyte | third instar larval stage phenotype of Hsap\HOXA9::Hsap\NUP98^WT.UAS, Scer\GAL4^Hml.Δ

(Baril et al., 2017)

Other

Statement

Reference

Scer\GAL4^GMR.PFa, hth^KK108831, yki^{S111A.S168A.S250A.UAS.Tag:V5} has eye disc | larval stage phenotype

(Rader et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Larvae co-expressing hth^KK108831 and exd^GD1439 under the control of Scer\GAL4^Hml.Δ do not show changes in the number of lymph gland hemocytes, as compared to controls.

(Baril et al., 2017)

Expression of hth^KK108831 is unable to suppress the increase in glial cell number seen in larval eye discs expressing yki^{S168A.Scer\UAS.T:SV5\V5} under the control of Scer\GAL4^repo.PU.

(Reddy and Irvine, 2011)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v100630

P{KK108831}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

hth^KK108831

(Paul et al., 2021)

Name Synonyms

Secondary FlyBase IDs

References (12)

Report Sections

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