FB2025_01 , released February 20, 2025
Allele: Dmel\Ref1KK109076
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General Information
Symbol
Dmel\Ref1KK109076
Species
D. melanogaster
Name
FlyBase ID
FBal0236030
Feature type
allele
Associated gene
Dmel\Ref1
Associated Insertion(s)
Carried in Construct
P{KK109076}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
in vitro construct
(Keleman et al., 2009.8.5)
Progenitor genotype
Carried in construct
P{KK109076}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-KK109076
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      DOES NOT ameliorate  amyotrophic lateral sclerosis
      modeled by Zzzz\GGGGCC36.UAS
      (Hautbergue et al., 2017)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      Ref1KK109076, Scer\GAL4GMR.PF is a non-suppressor of eye | adult stage phenotype of Scer\GAL4GMR.PF, Zzzz\GGGGCC36.UAS

      (Hautbergue et al., 2017)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      The co-expression of Ref1KK109076 does not suppress the rough eye, the decreased adult locomotor activity or the decreased larval locomotor activity induced by the expression of Zzzz\GGGGCC36.Scer\UAS under the control of Scer\GAL4GMR.PF, Scer\GAL4da.G32, and Scer\GAL4nSyb.PS, respectively.

      (Hautbergue et al., 2017)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      AlyKK109076
      Ref1KK109076
      Name Synonyms
      Secondary FlyBase IDs
        References (6)