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General Information
Symbol
Dmel\M6KK109436
Species
D. melanogaster
Name
FlyBase ID
FBal0236318
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of M6KK109436 under the control of Scer\GAL4Act5C.PU results in pupal lethality.

Expression of M6KK109436 under the control of Scer\GAL4Bx-MS1096 results in diminished wing size, abnormal curling, and loss of one or both cross veins.

Expression of M6KK109436 under the control of Scer\GAL4repo.PU, Scer\GAL4GMR.PU or Scer\GAL4elav.PU does not lead to lethality or morphological changes.

Expression of M6KK109436 under the control of Scer\GAL4Mef2.247 does not lead to significant learning or memory defects.

Expression of M6KK109436 under the control of Scer\GAL4dm-PG45 in adult females (using the temperature sensitive Scer\GAL80ts.αTub84B allele to restrict expression) results in a reduction in female fertility compared to controls after shifting to 29[o]C. There is also an increase in the percentage of permeable eggs laid by these females compared to those laid at 18[o]C. The permeable egg phenotype is reversible upon shifting back to 18[o]C.

Females expressing M6NIG.7540R under the control of Scer\GAL4dm-PG45 at 32[o]C for 72 hours (to inactivate the temperature-sensitive Scer\GAL80ts.αTub84B repressor) show a clear disruption in oogenesis, with no egg chambers between stages 9 to 13 being identifiable. In addition, both polar and border cells do not migrate in stage 9 egg chambers and remain at the anterior region.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
M6KK109436
Name Synonyms
Secondary FlyBase IDs
    References (3)