FlyBase Allele Report: Dmel\yki[KK109756]

The expression of yki^KK109756 under the control of Scer\GAL4^Mef2.PR leads to indirect flight muscle atrophy during pupal development (after 48h APF); fibers are longer than in controls, failing to compact at 24h APF. Expression from pupal stages onward (by the additional control of Gal80[ts[) leads to similar defects.

(Kaya-Çopur et al., 2021)

Expressing yki^KK109756 under the control of Scer\GAL4^ptc-559.1 results in a significant reduction of the anterior-posterior compartment boundary of the wing disc, while expression under the control of Scer\GAL4^hh-Gal4 causes a severe reduction of the wing disc posterior compartment in third instar larvae.

(Mach et al., 2018)

In the ventral nerve cord of third instar larvae, somatic clones of type I lineages expressing yki^KK109756 under the control of Scer\GAL4^Tub.PU have an overall decreased volume compared to controls.

Expressing yki^KK109756 under the control of Scer\GAL4^insc-Mz1407 has no effect on central nervous system size or neuroblast proliferation in late-first/early-second instar larvae.

(Poon et al., 2016)

The expression of yki^KK109756 under the control of Scer\GAL4^Bx-MS1096 does not lead to obvious size defects in third instar larval wing discs, as compared to controls.

(Bunker et al., 2015)

Expression of yki^KK109756 under the control of Scer\GAL4^C587 results in tumorous female germaria with ectopic germline stem cell/cystoblast-like cells.

(Li et al., 2015)

Wings discs expressing yki^KK109756 under the control of Scer\GAL4^en-e16E at 18[o]C are similar in size to controls.

(Boggiano et al., 2011)

The brain and ventral nerve cord of flies expressing yki^KK109756 under the control of Scer\GAL4^repo.PU are reduced in size and contain fewer glial cells. Total brain volume is reduced. Third instar larval eye discs also contain fewer glial cells, having on average 66 in comparison with the 105 seen in wild-type.

(Reddy and Irvine, 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^nub.PU, yki^KK109756 has visible | adult stage phenotype, enhanceable by RpS3[+]/RpS3^Plac92

(Wada et al., 2021)

Scer\GAL4^nub.PU, yki^KK109756 has decreased size | adult stage phenotype, enhanceable by RpS3[+]/RpS3^Plac92

(Wada et al., 2021)

Suppressed by

Statement

Reference

Scer\GAL4^Mef2.PR, yki^KK109756 has atrophy | pupal stage phenotype, suppressible | partially by Diap1^UAS.cHa, Scer\GAL4^Mef2.PR

(Kaya-Çopur et al., 2021)

Scer\GAL4^Mef2.PR, yki^KK109756 has atrophy | pupal stage phenotype, suppressible | partially by BacA\p35^UAS.cHa, Scer\GAL4^Mef2.PR

(Kaya-Çopur et al., 2021)

Scer\GAL4^GMR.PU, hid^GMR.PG, yki^KK109756 has lethal | pharate adult stage phenotype, suppressible by Ack^UAS.cSb, Scer\GAL4^GMR.PU

(Schoenherr et al., 2012)

NOT suppressed by

Statement

Reference

Scer\GAL4^Mef2.PR, yki^KK109756 has decreased cell number | pupal stage phenotype, non-suppressible by Moe^{GMA.UAS.GFP(S65T)}, Scer\GAL4^Mef2.PR

(Kaya-Çopur et al., 2021)

Scer\GAL4^Tub.PU, Scer\GAL80^ts.αTub84B, yki^KK109756 has abnormal neuroanatomy | somatic clone | third instar larval stage phenotype, non-suppressible by wts^x1/wts^x1

(Poon et al., 2016)

Scer\GAL4^Tub.PU, Scer\GAL80^ts.αTub84B, yki^KK109756 has abnormal size | somatic clone | third instar larval stage phenotype, non-suppressible by wts^x1/wts^x1

(Poon et al., 2016)

Suppressor of

Statement

Reference

yki^KK109756/Scer\GAL4^NP0001 is a suppressor | partially of increased occurrence of cell division | recessive | adult stage phenotype of SH3PX1^d1

(Zhang et al., 2019)

yki^KK109756/Scer\GAL4^rn.PU is a suppressor | partially of abnormal developmental rate phenotype of Scer\GAL4^rn.PU, Syx7^KK101990

(Boone et al., 2016)

yki^KK109756/Scer\GAL4^insc-Mz1407 is a suppressor of abnormal neuroanatomy | first instar larval stage phenotype of Scer\GAL4^insc-Mz1407, Tao^GD8262

(Poon et al., 2016)

yki^KK109756/Scer\GAL4^insc-Mz1407 is a suppressor of abnormal neuroanatomy | second instar larval stage phenotype of Scer\GAL4^insc-Mz1407, Tao^GD8262

(Poon et al., 2016)

yki^KK109756/Scer\GAL4^insc-Mz1407 is a suppressor of abnormal size | first instar larval stage phenotype of Scer\GAL4^insc-Mz1407, Tao^GD8262

(Poon et al., 2016)

yki^KK109756/Scer\GAL4^insc-Mz1407 is a suppressor of abnormal size | second instar larval stage phenotype of Scer\GAL4^insc-Mz1407, Tao^GD8262

(Poon et al., 2016)

yki^KK109756, Scer\GAL4^Tub.PU, Scer\GAL80^ts.αTub84B is a suppressor of abnormal neuroanatomy | somatic clone | third instar larval stage phenotype of wts^x1

(Poon et al., 2016)

yki^KK109756, Scer\GAL4^Tub.PU, Scer\GAL80^ts.αTub84B is a suppressor of abnormal size | somatic clone | third instar larval stage phenotype of wts^x1

(Poon et al., 2016)

yki^KK109756/Scer\GAL4^en-e16E is a suppressor of abnormal size | third instar larval stage phenotype of Scer\GAL4^en-e16E, Tao^GD8262

(Boggiano et al., 2011)

yki^KK109756, Scer\GAL4^repo.PU is a suppressor of increased cell number | third instar larval stage phenotype of Mer^GD1484, Scer\GAL4^repo.PU

(Reddy and Irvine, 2011)

NOT Suppressor of

Statement

Reference

yki^KK109756/Scer\GAL4^repo.PU is a non-suppressor of increased cell number | third instar larval stage phenotype of Scer\GAL4^repo.PU, mir-ban^GS

(Reddy and Irvine, 2011)

Other

Statement

Reference

Scer\GAL4^Tub.PU, Scer\GAL80^ts.αTub84B, wts^x1, yki^KK109756 has abnormal neuroanatomy | somatic clone | third instar larval stage phenotype

(Poon et al., 2016)

Scer\GAL4^Tub.PU, Scer\GAL80^ts.αTub84B, wts^x1, yki^KK109756 has abnormal size | somatic clone | third instar larval stage phenotype

(Poon et al., 2016)

Ack^UAS.cSb, Scer\GAL4^GMR.PU, hid^Ala5.GMR, yki^KK109756 has lethal phenotype

(Schoenherr et al., 2012)

Scer\GAL4^GMR.PU, hid^GMR.PG, yki^KK109756 has lethal | pharate adult stage phenotype

(Schoenherr et al., 2012)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^nub.PU, yki^KK109756 has wing phenotype, enhanceable by RpS3[+]/RpS3^Plac92

(Wada et al., 2021)

Suppressed by

Statement

Reference

Scer\GAL4^Mef2.PR, yki^KK109756 has indirect flight muscle cell | pupal stage phenotype, suppressible | partially by BacA\p35^UAS.cHa, Scer\GAL4^Mef2.PR

(Kaya-Çopur et al., 2021)

Scer\GAL4^Mef2.PR, yki^KK109756 has indirect flight muscle cell | pupal stage phenotype, suppressible | partially by Diap1^UAS.cHa, Scer\GAL4^Mef2.PR

(Kaya-Çopur et al., 2021)

NOT suppressed by

Statement

Reference

Scer\GAL4^Mef2.PR, yki^KK109756 has indirect flight muscle cell | pupal stage phenotype, non-suppressible by Moe^{GMA.UAS.GFP(S65T)}, Scer\GAL4^Mef2.PR

(Kaya-Çopur et al., 2021)

Scer\GAL4^Tub.PU, Scer\GAL80^ts.αTub84B, yki^KK109756 has larval ventral nerve cord | somatic clone | third instar larval stage phenotype, non-suppressible by wts^x1/wts^x1

(Poon et al., 2016)

Suppressor of

Statement

Reference

yki^KK109756/Scer\GAL4^GMR.long is a suppressor of photoreceptor cell R8 phenotype of Scer\GAL4^GMR.long, kst^HMS00882

(Pojer et al., 2021)

yki^KK109756, Scer\GAL4^GMR.long is a suppressor of photoreceptor cell R8 phenotype of α-Spec^GD9695, Scer\GAL4^GMR.long

(Pojer et al., 2021)

yki^KK109756/Scer\GAL4^GMR.long is a suppressor of photoreceptor cell R8 phenotype of Scer\GAL4^GMR.long, crb^intra.UAS

(Pojer et al., 2021)

yki^KK109756/Scer\GAL4^NP0001 is a suppressor | partially of adult midgut epithelium phenotype of SH3PX1^d1

(Zhang et al., 2019)

yki^KK109756/Scer\GAL4^insc-Mz1407 is a suppressor of larval central nervous system | first instar larval stage phenotype of Scer\GAL4^insc-Mz1407, Tao^GD8262

(Poon et al., 2016)

yki^KK109756/Scer\GAL4^insc-Mz1407 is a suppressor of larval central nervous system | second instar larval stage phenotype of Scer\GAL4^insc-Mz1407, Tao^GD8262

(Poon et al., 2016)

yki^KK109756/Scer\GAL4^insc-Mz1407 is a suppressor of type I neuroblast | first instar larval stage phenotype of Scer\GAL4^insc-Mz1407, Tao^GD8262

(Poon et al., 2016)

yki^KK109756/Scer\GAL4^insc-Mz1407 is a suppressor of type I neuroblast | second instar larval stage phenotype of Scer\GAL4^insc-Mz1407, Tao^GD8262

(Poon et al., 2016)

yki^KK109756, Scer\GAL4^Tub.PU, Scer\GAL80^ts.αTub84B is a suppressor of larval ventral nerve cord | somatic clone | third instar larval stage phenotype of wts^x1

(Poon et al., 2016)

yki^KK109756/Scer\GAL4^en-e16E is a suppressor of wing disc | third instar larval stage phenotype of Scer\GAL4^en-e16E, Tao^GD8262

(Boggiano et al., 2011)

yki^KK109756, Scer\GAL4^repo.PU is a suppressor of larval glial cell | third instar larval stage phenotype of Mer^GD1484, Scer\GAL4^repo.PU

(Reddy and Irvine, 2011)

yki^KK109756, Scer\GAL4^repo.PU is a suppressor of eye disc | third instar larval stage phenotype of Mer^GD1484, Scer\GAL4^repo.PU

(Reddy and Irvine, 2011)

NOT Suppressor of

Statement

Reference

yki^KK109756/Scer\GAL4^repo.PU is a non-suppressor of eye disc | third instar larval stage phenotype of Scer\GAL4^repo.PU, mir-ban^GS

(Reddy and Irvine, 2011)

yki^KK109756/Scer\GAL4^repo.PU is a non-suppressor of larval glial cell | third instar larval stage phenotype of Scer\GAL4^repo.PU, mir-ban^GS

(Reddy and Irvine, 2011)

Other

Statement

Reference

α-Spec^GD9695, Scer\GAL4^GMR.long, yki^KK109756 has photoreceptor cell R8 phenotype

(Pojer et al., 2021)

Scer\GAL4^GMR.long, crb^intra.UAS, yki^KK109756 has photoreceptor cell R8 phenotype

(Pojer et al., 2021)

Scer\GAL4^GMR.long, kst^HMS00882, yki^KK109756 has photoreceptor cell R8 phenotype

(Pojer et al., 2021)

Scer\GAL4^Tub.PU, Scer\GAL80^ts.αTub84B, wts^x1, yki^KK109756 has larval ventral nerve cord | somatic clone | third instar larval stage phenotype

(Poon et al., 2016)

Additional Comments

Genetic Interactions

Statement

Reference

The co-expression of yki^KK109756 suppresses the increased ratio of pale vs yellow photoreceptor cells R8 induced by the expression of either α-Spec^GD9695, kst^HMS00882 or crb^intra.UAS under the control of Scer\GAL4^GMR.long, even leading to all photoreceptor cells R8 becoming the yellow type.

(Pojer et al., 2021)

The marked delay in pupariation characteristic for larvae expressing Syx7^KK101990 under the control of Scer\GAL4^rn.PU can be partially suppressed by co-expression of yki^KK109756.

(Boone et al., 2016)

Expression of yki^KK109756 suppresses the wing disc over-proliferation phenotype seen when Tao^GD8262 is expressed under the control of Scer\GAL4^en-e16E at 18[o]C.

(Boggiano et al., 2011)

Expression of yki^KK109756 suppresses the increase in glial cell number seen in third instar larval eye discs expressing Mer^GD1484 under the control of Scer\GAL4^repo.PU.

Expression of yki^KK109756 does not suppress the increase in glial cell number seen in the larval eye disc when ban^GS is expressed under the control of Scer\GAL4^repo.PU.

(Reddy and Irvine, 2011)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v104523

P{KK109756}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

yki^KK109756

Name Synonyms

Secondary FlyBase IDs

References (36)

Report Sections

Open Close