Open Close
General Information
Symbol
Dmel\ykiKK109756
Species
D. melanogaster
Name
FlyBase ID
FBal0236466
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-yki RNAi, yki RNAi, yki-RNAi, UAS-RNAi-yki, UAS-ykiRNAi
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expressing ykiKK109756 under the control of Scer\GAL4ptc-559.1 results in a significant reduction of the anterior-posterior compartment boundary of the wing disc, while expression under the control of Scer\GAL4hh-Gal4 causes a severe reduction of the wing disc posterior compartment in third instar larvae.

In the ventral nerve cord of third instar larvae, somatic clones of type I lineages expressing ykiKK109756 under the control of Scer\GAL4Tub.PU have an overall decreased volume compared to controls.

Expressing ykiKK109756 under the control of Scer\GAL4insc-Mz1407 has no effect on central nervous system size or neuroblast proliferation in late-first/early-second instar larvae.

The expression of ykiKK109756 under the control of Scer\GAL4Bx-MS1096 does not lead to obvious size defects in third instar larval wing discs, as compared to controls.

Expression of ykiKK109756 under the control of Scer\GAL4C587 results in tumorous female germaria with ectopic germline stem cell/cystoblast-like cells.

Wings discs expressing ykiKK109756 under the control of Scer\GAL4en-e16E at 18[o]C are similar in size to controls.

The brain and ventral nerve cord of flies expressing ykiKK109756 under the control of Scer\GAL4repo.PU are reduced in size and contain fewer glial cells. Total brain volume is reduced. Third instar larval eye discs also contain fewer glial cells, having on average 66 in comparison with the 105 seen in wild-type.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
NOT suppressed by
Suppressor of
Statement
Reference
NOT Suppressor of
Other
Phenotype Manifest In
NOT suppressed by
Suppressor of
NOT Suppressor of
Other
Additional Comments
Genetic Interactions
Statement
Reference

The marked delay in pupariation characteristic for larvae expressing Syx7KK101990 under the control of Scer\GAL4rn.PU can be partially suppressed by co-expression of ykiKK109756.

Expression of ykiKK109756 suppresses the wing disc over-proliferation phenotype seen when TaoGD8262 is expressed under the control of Scer\GAL4en-e16E at 18[o]C.

Expression of ykiKK109756 suppresses the increase in glial cell number seen in third instar larval eye discs expressing MerGD1484 under the control of Scer\GAL4repo.PU.

Expression of ykiKK109756 does not suppress the increase in glial cell number seen in the larval eye disc when banGS is expressed under the control of Scer\GAL4repo.PU.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
ykiKK109756
Name Synonyms
Secondary FlyBase IDs
    References (22)