FlyBase Allele Report: Dmel\Zip88E[KK110168]

General Information

Symbol

Dmel\Zip88E^KK110168

Species

D. melanogaster

Name

FlyBase ID

FBal0236690

Feature type

allele

Associated gene

Dmel\Zip88E

Associated Insertion(s)

Carried in Construct

P{KK110168}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK110168}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK110168

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates Friedreich ataxia 1

modeled by fh^RNAi.UAS.cAa

(Soriano et al., 2016)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Zip88E^KK110168/Scer\GAL4^GMR.long is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.cDa

(Dechen et al., 2015)

Zip88E^KK110168/Scer\GAL4^GMR.long is a suppressor | partially of abnormal eye color phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.cDa

(Dechen et al., 2015)

Zip88E^KK110168/Scer\GAL4^GMR.long is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.EGFP

(Dechen et al., 2015)

Zip88E^KK110168/Scer\GAL4^GMR.long is a suppressor | partially of abnormal eye color phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.EGFP

(Dechen et al., 2015)

Zip88E^KK110168/Scer\GAL4^GMR.long is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4^GMR.long, Zip71B^UAS.Tag:FLAG

(Dechen et al., 2015)

Zip88E^KK110168/Scer\GAL4^GMR.long is a suppressor | partially of abnormal eye color phenotype of Scer\GAL4^GMR.long, Zip71B^UAS.Tag:FLAG

(Dechen et al., 2015)

NOT Suppressor of

Statement

Reference

Zip88E^KK110168/Scer\GAL4^GMR.long is a non-suppressor | partially of visible | adult stage phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.EGFP

(Dechen et al., 2015)

Phenotype Manifest In

Suppressor of

Statement

Reference

Zip88E^KK110168/Scer\GAL4^GMR.long is a suppressor | partially of eye phenotype of Scer\GAL4^GMR.long, Zip71B^UAS.Tag:FLAG

(Dechen et al., 2015)

Zip88E^KK110168/Scer\GAL4^GMR.long is a suppressor | partially of eye phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.cDa

(Dechen et al., 2015)

Zip88E^KK110168/Scer\GAL4^GMR.long is a suppressor | partially of eye phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.EGFP

(Dechen et al., 2015)

NOT Suppressor of

Statement

Reference

Zip88E^KK110168/Scer\GAL4^GMR.long is a non-suppressor | partially of eye phenotype of Scer\GAL4^GMR.long, ZnT86D^UAS.EGFP

(Dechen et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

The morphological and pigmentation defects in the adult eye seen upon expression of ZnT86D^Scer\UAS.cDa under the control of Scer\GAL4^GMR.long are mildly ameliorated by co-expression of Zip88E^KK110168.

The adult eye phenotype seen upon expression of ZnT86D^{Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.long can be partially modified by co-expression of Zip88E^KK110168 RNAi: the morphological defects are unchanged the pigmentation loss is mildly ameliorated.

The morphological and pigmentation defects in the adult eye seen upon expression of Zip71B^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.long are strongly ameliorated by co-expression of Zip88E^KK110168 RNAi.

(Dechen et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v106785

P{KK110168}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

CG4334^KK110168

Zip88E^KK110168

Zip88E^shRNA

(Soriano et al., 2016)

dZip88E^RNAi

(Dechen et al., 2015)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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