FlyBase Allele Report: Dmel\pkm[KK110542]

General Information

Symbol

Dmel\pkm^KK110542

Species

D. melanogaster

Name

FlyBase ID

FBal0236914

Feature type

allele

Associated gene

Dmel\pkm

Associated Insertion(s)

Carried in Construct

P{KK110542}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK110542}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK110542

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates brain cancer

modeled by Ras85D^V12.cUa.UAS, scrib⁶⁷³

(Manzanero-Ortiz et al., 2021)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

embryonic/larval neuromuscular junction | third instar larval stage, with Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

presynaptic active zone | increased number | third instar larval stage, with Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^Toll-6-D42, pkm^KK110542 has presynaptic active zone | third instar larval stage | increased number phenotype, enhanceable by Hsp23^UAS.cKa/Hsp26^{UAS.ORF.Tag:HA}, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Scer\GAL4^Toll-6-D42, pkm^KK110542 has embryonic/larval neuromuscular junction | third instar larval stage phenotype, enhanceable by Hsp23^UAS.cKa/Hsp26^{UAS.ORF.Tag:HA}, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Scer\GAL4^Toll-6-D42, pkm^KK110542 has presynaptic active zone | third instar larval stage | increased number phenotype, enhanceable by Hsp26^{UAS.ORF.Tag:HA}, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Scer\GAL4^Toll-6-D42, pkm^KK110542 has embryonic/larval neuromuscular junction | third instar larval stage phenotype, enhanceable by Hsp26^{UAS.ORF.Tag:HA}, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

NOT Enhanced by

Statement

Reference

Scer\GAL4^Toll-6-D42, pkm^KK110542 has presynaptic active zone | third instar larval stage | increased number phenotype, non-enhanceable by Hsp23^KK111816, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Scer\GAL4^Toll-6-D42, pkm^KK110542 has embryonic/larval neuromuscular junction | third instar larval stage phenotype, non-enhanceable by Hsp23^KK111816, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Scer\GAL4^Toll-6-D42, pkm^KK110542 has presynaptic active zone | third instar larval stage | increased number phenotype, non-enhanceable by Hsp23^UAS.cKa, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Scer\GAL4^Toll-6-D42, pkm^KK110542 has embryonic/larval neuromuscular junction | third instar larval stage phenotype, non-enhanceable by Hsp23^UAS.cKa, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Scer\GAL4^Toll-6-D42, pkm^KK110542 has presynaptic active zone | third instar larval stage | increased number phenotype, non-enhanceable by Hsp26^GL00329/Hsp23^KK111816, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Scer\GAL4^Toll-6-D42, pkm^KK110542 has embryonic/larval neuromuscular junction | third instar larval stage phenotype, non-enhanceable by Hsp26^GL00329/Hsp23^KK111816, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

NOT suppressed by

Statement

Reference

Scer\GAL4^Toll-6-D42, pkm^KK110542 has presynaptic active zone | increased number | third instar larval stage phenotype, non-suppressible by Hsp23^UAS.cKa, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Scer\GAL4^Toll-6-D42, pkm^KK110542 has embryonic/larval neuromuscular junction | third instar larval stage phenotype, non-suppressible by Hsp23^UAS.cKa, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Scer\GAL4^Toll-6-D42, pkm^KK110542 has presynaptic active zone | increased number | third instar larval stage phenotype, non-suppressible by Hsp26^GL00329/Hsp23^KK111816, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Scer\GAL4^Toll-6-D42, pkm^KK110542 has embryonic/larval neuromuscular junction | third instar larval stage phenotype, non-suppressible by Hsp26^GL00329/Hsp23^KK111816, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Scer\GAL4^Toll-6-D42, pkm^KK110542 has presynaptic active zone | increased number | third instar larval stage phenotype, non-suppressible by Hsp23^KK111816, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Scer\GAL4^Toll-6-D42, pkm^KK110542 has embryonic/larval neuromuscular junction | third instar larval stage phenotype, non-suppressible by Hsp23^KK111816, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

NOT Enhancer of

Statement

Reference

pkm^KK110542, Scer\GAL4^Toll-6-D42 is a non-enhancer of presynaptic active zone | third instar larval stage | increased number phenotype of Hsp23^UAS.cKa, Hsp26^{UAS.ORF.Tag:HA}, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

pkm^KK110542, Scer\GAL4^Toll-6-D42 is a non-enhancer of embryonic/larval neuromuscular junction | third instar larval stage phenotype of Hsp23^UAS.cKa, Hsp26^{UAS.ORF.Tag:HA}, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

NOT Suppressor of

Statement

Reference

pkm^KK110542, Scer\GAL4^Toll-6-D42 is a non-suppressor of presynaptic active zone | increased number | third instar larval stage phenotype of Hsp23^UAS.cKa, Hsp26^{UAS.ORF.Tag:HA}, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

pkm^KK110542, Scer\GAL4^Toll-6-D42 is a non-suppressor of embryonic/larval neuromuscular junction | third instar larval stage phenotype of Hsp23^UAS.cKa, Hsp26^{UAS.ORF.Tag:HA}, Scer\GAL4^Toll-6-D42

(Santana et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v106503

P{KK110542}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG1561^KK110542

pkm^KK110542

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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