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General Information
Symbol
Dmel\AcnKK111555
Species
D. melanogaster
Name
FlyBase ID
FBal0237496
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Fed or starved larvae experiencing knockdown of both Dcp-1 and Acn (through expression of Dcp-1GD10729 and AcnKK111555 under the control of Scer\GAL4da.G32), display wild-type levels of autophagy, indicating that the remaining protein after Acn knockdown is sufficient to support starvation-induced autophagy but not sufficient to drive elevated levels of basal autophagy in a fed Dcp-1 background.

Xenogenetic Interactions
Statement
Reference

Knockdown of Acn, through expression of AcnKK111555 under the control of Scer\GAL4GMR.PF enhances the neuronal degeneration and depolarization seen in flies expressing Hsap\HTTQ93.ex1p.Scer\UAS.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
AcnKK111555
hklKK111555
Name Synonyms
Secondary FlyBase IDs
    References (4)