FlyBase Allele Report: Dmel\Ilp6[KK111727]

General Information

Symbol

Dmel\Ilp6^KK111727

Species

D. melanogaster

Name

FlyBase ID

FBal0237623

Feature type

allele

Associated gene

Dmel\Ilp6

Associated Insertion(s)

Carried in Construct

P{KK111727}

Also Known As

UAS-dilp6^RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK111727}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK111727

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased body size | adult stage, with Scer\GAL4^Cg.PA

(Slaidina et al., 2009)

decreased cell number | third instar larval stage, with Scer\GAL4^Mef2.PR

(Aradhya et al., 2015)

Phenotype Manifest In

abdominal dorsal adult muscle precursor cell | third instar larval stage, with Scer\GAL4^Mef2.PR

(Aradhya et al., 2015)

abdominal lateral adult muscle precursor cell | third instar larval stage, with Scer\GAL4^Mef2.PR

(Aradhya et al., 2015)

Detailed Description

Statement

Reference

Expression of Ilp6^KK111727 under the control of Scer\GAL4^Mef2.PR, but not of Scer\GAL4^repo, leads to significantly decreased numbers of abdominal lateral and dorsal, but not ventral, adult muscle precursor cells in third instar larvae, as compared to controls; expression under the control of Scer\GAL4^repo has no effect on the number of abdominal adult muscle precursor cells, as compared to controls.

(Aradhya et al., 2015)

Expression of Ilp6^KK111727 under the control of Scer\GAL4^Cg.PA results in adults that have a smaller mass than controls.

(Slaidina et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v102465

P{KK111727}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Ilp6^KK111727

dilp6^RNAi

(Chatterjee et al., 2014)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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