Allele Dmel\E(spl)m4-BFM^{4KR.Scer\UAS.T:Zzzz\FLAG}

General Information
Symbol	Dmel\E(spl)m4-BFM^{4KR.Scer\UAS.T:Zzzz\FLAG}	Species	D. melanogaster
Name		FlyBase ID	FBal0239173
Feature type	allele	Associated gene	Dmel\E(spl)m4-BFM

Allele class
Mutagen	in vitro construct - amino acid replacement
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	in vitro construct - amino acid replacement (Fontana and Posakony, 2009)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	E(spl)m4-BFM^{Scer\UAS.T:Zzzz\FLAG} (Fontana and Posakony, 2009)
Nature of the lesion	Statement Reference Mutation of the four Lys residues of the B domain to Arg. (Fontana and Posakony, 2009)
Carried in construct	P{UAS-FLAG-m4.4KR} (Fontana and Posakony, 2009)
Tagged with	T:Zzzz\FLAG (Fontana and Posakony, 2009)
Cytology
Phenotypic Data
Phenotypic Class
	visible, with Scer\GAL4^sca-537.4 (Fontana and Posakony, 2009)
Phenotype Manifest In
	macrochaeta \| ectopic, with Scer\GAL4^sca-537.4 (Fontana and Posakony, 2009)
Detailed Description
	Statement Reference Expression of m4[4KR.Scer\UAS.T:Zzzz\FLAG] under the control of Scer\GAL4[sca-537.4] results in the production of extra bristles (average 23 extra bristles per fly, total of 26 bristle positions on the notum and head assayed). (Fontana and Posakony, 2009)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	E(spl)m4-BFM^{4KR.Scer\UAS.T:Zzzz\FLAG} m4^{4KR.Scer\UAS.T:Zzzz\FLAG}
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Fontana and Posakony, 2009, Dev. Biol. 333(2): 373--385 Both inhibition and activation of Notch signaling rely on a conserved Neuralized-binding motif in Bearded proteins and the Notch ligand Delta. [FBrf0208547]

Allele Dmel\E(spl)m4-BFM4KR.Scer\UAS.T:Zzzz\FLAG

Allele Dmel\E(spl)m4-BFM^{4KR.Scer\UAS.T:Zzzz\FLAG}