UAS regulatory sequences drive expression of an inverted repeat.
Expressing uspJF02546 under the control of Scer\GAL4GMR71G10 leads to a small frequency of mushroom body gamma neuron pruning defects.
Expression of uspJF02546 in muscle under the control of Scer\GAL4Mef2.PU results in significant hyperglycaemia.
Expression of uspJF02546 under the control of Scer\GAL4phm.PO results in larvae that undergo the 'critical weight' ecdysone peak at reduced sizes compared to controls in response to starvation. It occurs at the same age as control flies.
Expression of uspJF02546 under the control of Scer\GAL4phm.PO in starved larvae results in pharate adults with a significantly reduced body size compared with controls.
Scer\GAL4phtm.PO, uspJF02546 has decreased body size | pharate adult stage | nutrition conditional phenotype, enhanceable by foxoKK108590/Scer\GAL4phtm.PO
uspJF02546/Scer\GAL4phtm.PO is an enhancer of decreased body size | pharate adult stage phenotype of Scer\GAL4phtm.PO, foxoKK108590
Scer\GAL4phtm.PO, foxoKK108590, uspJF02546 has abnormal developmental rate | nutrition conditional phenotype
Co-expression of uspJF02546 and foxoKK108590 under the control of Scer\GAL4phm.PO enhances the increase in size at which the 'critical weight' ecdysone peak takes place in response to starvation compared to that seen with either transgene alone. The critical weight takes place significantly earlier than in controls.
Co-expression of foxoKK108590 and uspJF02546 under the control of Scer\GAL4phm.PO in starved larvae dramatically enhances the reduction in pharate adult body size seen with either transgene alone.
