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General Information
Symbol
Dmel\AP-2σJF02631
Species
D. melanogaster
Name
FlyBase ID
FBal0239331
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UAS regulatory sequences drive expression of an inverted repeat.
Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Expression of AP-2σJF02631 under the control of Scer\GAL4ey.PU results in a range of eye defects. Expression under the control of Scer\GAL4Act5C.PU results in sluggish 3rd instar larvae which die. Expression under the control of Scer\GAL4elav-C155 results in adult paralysis under 37[o]C conditions. Expression under the control of Scer\GAL4Toll-6-D42 leads to normal adults. Expression under the control of Scer\GAL4elav-C155 (and Dicer-2, for efficient RNAi) also leads to a significant increase in the number of boutons at the larval muscle 6/7 NMJs, and leads to a significant decline in EJP amplitude readings upon high-frequency stimulation at 34[o]C conditions even after a 4min rest period, as compared to controls.
Expression of AP-2σJF02631 in muscle under the control of Scer\GAL4Mef2.PU results in significant hyperglycaemia.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
AP-2σJF02631
Name Synonyms
Secondary FlyBase IDs
    References (5)