FlyBase Allele Report: Dmel\nanos[JF02931]

General Information

Symbol

Dmel\nanos^JF02931

Species

D. melanogaster

Name

FlyBase ID

FBal0239436

Feature type

allele

Associated gene

Dmel\nanos

Associated Insertion(s)

Carried in Construct

P{TRiP.JF02931}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

(Perkins et al., 2009)

Progenitor genotype

Carried in construct

P{TRiP.JF02931}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-JF02931

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of nos^JF02931 under the control of Scer\GAL4^GMR.PU does not result in any obvious phenotype in the adult eye or third instar larval wing disc, as compared to controls.

(Zhang et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^en.PU/nanos^JF02931 is a suppressor | partially of abnormal size | third instar larval stage phenotype of Scer\GAL4^en.PU, yki^UAS.cHa

(Zhang et al., 2015)

nanos^JF02931/Scer\GAL4^GMR.PU is a suppressor of abnormal size | adult stage phenotype of Scer\GAL4^GMR.PU, yki^{S168A.UAS.YFP}

(Zhang et al., 2015)

nanos^JF02931/Scer\GAL4^GMR.PU is a suppressor of visible phenotype of Scer\GAL4^GMR.PU, yki^{S168A.UAS.YFP}

(Zhang et al., 2015)

Other

Statement

Reference

Rbf^HMS03004, Scer\GAL4^nub.PU, nanos^JF02931 has visible | adult stage phenotype

(Miles et al., 2014)

E2f2^JF02828, Scer\GAL4^nub.PU, nanos^JF02931 has visible | adult stage phenotype

(Miles et al., 2014)

Scer\GAL4^nub.PU, mip120^HMS00461, nanos^JF02931 has visible | adult stage phenotype

(Miles et al., 2014)

Scer\GAL4^nub.PU, mip130^HMS00462, nanos^JF02931 has visible | adult stage phenotype

(Miles et al., 2014)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^en.PU/nanos^JF02931 is a suppressor | partially of wing disc posterior compartment | third instar larval stage phenotype of Scer\GAL4^en.PU, yki^UAS.cHa

(Zhang et al., 2015)

nanos^JF02931/Scer\GAL4^GMR.PU is a suppressor of eye phenotype of Scer\GAL4^GMR.PU, yki^{S168A.UAS.YFP}

(Zhang et al., 2015)

Other

Statement

Reference

Rbf^HMS03004, Scer\GAL4^nub.PU, nanos^JF02931 has wing blade phenotype

(Miles et al., 2014)

Scer\GAL4^nub.PU, mip130^HMS00462, nanos^JF02931 has wing blade phenotype

(Miles et al., 2014)

E2f2^JF02828, Scer\GAL4^nub.PU, nanos^JF02931 has wing vein | ectopic phenotype

(Miles et al., 2014)

E2f2^JF02828, Scer\GAL4^nub.PU, nanos^JF02931 has wing blade phenotype

(Miles et al., 2014)

Scer\GAL4^nub.PU, mip120^HMS00461, nanos^JF02931 has wing vein | ectopic phenotype

(Miles et al., 2014)

Scer\GAL4^nub.PU, mip120^HMS00461, nanos^JF02931 has wing blade phenotype

(Miles et al., 2014)

Scer\GAL4^nub.PU, mip130^HMS00462, nanos^JF02931 has wing vein | ectopic phenotype

(Miles et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of nos^JF02931 rescues the eye overgrowth seen in adults expressing yki^{S168A.Scer\UAS.T:Avic\GFP-YFP} under the control of Scer\GAL4^GMR.PU.

Co-expression of nos^JF02931 partially suppresses the wing disc posterior compartment overgrowth of larvae expressing yki^Scer\UAS.cHa under the control of Scer\GAL4^en.PU.

(Zhang et al., 2015)

Co-expression of any of the following: Rbf^HMS03004, E2f2^JF02828, mip130^HMS00462 or mip120^HMS00461 with nos^JF02931 under the control of Scer\GAL4^nub.PU (using UAS-Dicer2 to enhance RNAi efficiency) results in adult wing defects including blistering (with Rbf^HMS03004) and minor ectopic venation (with any of the others).

(Miles et al., 2014)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

28300

y¹ v¹; P{TRiP.JF02931}attP2/TM3, Sb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

nanos^JF02931

nos²⁸³⁰⁰

(Miles et al., 2014)

nos^IR

(Zhang et al., 2015)

nos^JF02931

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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