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General Information
Symbol
Dmel\ptcJF03223
Species
D. melanogaster
Name
FlyBase ID
FBal0239721
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
ptcRNAi, ptc-RNAi
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UAS regulatory sequences drive expression of an inverted repeat.
Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
The expression of ptcJF03223 under the control of Scer\GAL4109-30 leads to ovarioles frequently exhibiting multilayered stalks, as compared to controls.
Expression of ptcJF03223 driven by Scer\GAL4ptc.PU causes overgrowth of the A-P boundary, increasing distance between the L3 and L4 wing veins.
Expression of ptcJF03223 in clones in the wing disc results in overgrowth of the wing disc.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Other
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
The basal stalk multilayering observed upon the expression of ptcJF03223 under the control of Scer\GAL4109-30 is partially suppressed by the co-expression of Nhe2UAS.cGa, but not of Nhe2UAS.E358I.Tag:HA or Nhe2HMC03243.
Expression of ptcJF03223 under the control of Scer\GAL4C587 in flies expressing bamhs.PO induced via heat shock in a bamΔ86/bamΔ86 background suppresses the recovery of spectrosome-containing cells at 48 h after heat shock seen in flies expressing bamhs.PO alone in a bamΔ86/bamΔ86 background.
Co-expression of mir-14Scer\UAS.cLa.T:Disc\RFP suppresses the increased distance between the L3 and L4 wing veins seen in Scer\GAL4ptc.PU>ptcJF03223 flies; these flies even have a partial reduction in the distance between L3 and L4 (towards Scer\GAL4ptc.PU>mir-14Scer\UAS.cLa.T:Disc\RFP phenotypes, with a slight curving of the L4 vein towards the anterior portion of the wing).
ykiB5/+ suppresses the wing disc overgrowth caused by expression of ptcJF03223 in clones in the wing disc.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
ptcBL28795
ptcJF03223
Name Synonyms
Secondary FlyBase IDs
    References (9)