FlyBase Allele Report: Dmel\Rok[JF03225]

General Information

Symbol

Dmel\Rok^JF03225

Species

D. melanogaster

Name

FlyBase ID

FBal0239723

Feature type

allele

Associated gene

Dmel\Rok

Associated Insertion(s)

Carried in Construct

P{TRiP.JF03225}

Also Known As

UAS-Rok^RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

(Perkins et al., 2009)

Progenitor genotype

Carried in construct

P{TRiP.JF03225}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-JF03225

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

The expression of Rok^JF03225 under the control of Scer\GAL4^GMR.PU does not lead to significant changes in eye size, as compared to controls.

(Llavero Hurtado et al., 2017)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Rok^JF03225, Scer\GAL4^repo.PU is a suppressor of abnormal neuroanatomy | third instar larval stage phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo.PU, btl::Egfr^λ.UAS

(Chen et al., 2019)

Rok^JF03225, Scer\GAL4^repo.PU is a suppressor of neoplasia | third instar larval stage phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo.PU, btl::Egfr^λ.UAS

(Chen et al., 2019)

Rok^JF03225, Scer\GAL4^GMR.PU is a suppressor of abnormal size | adult stage phenotype of Cln3^UAS.cTa, Scer\GAL4^GMR.PU

(Llavero Hurtado et al., 2017)

Rok^JF03225, Scer\GAL4^GMR.PU is a suppressor of visible | adult stage phenotype of Cln3^UAS.cTa, Scer\GAL4^GMR.PU

(Llavero Hurtado et al., 2017)

Phenotype Manifest In

Enhancer of

Statement

Reference

Rok^JF03225/Scer\GAL4^GMR.PU is an enhancer of retina phenotype of eys¹, prom[+]/prom¹

(Nie et al., 2014)

Suppressor of

Statement

Reference

Rok^JF03225, Scer\GAL4^repo.PU is a suppressor of larval brain | third instar larval stage phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo.PU, btl::Egfr^λ.UAS

(Chen et al., 2019)

Rok^JF03225, Scer\GAL4^repo.PU is a suppressor of larval brain neuropil glial cell | third instar larval stage phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo.PU, btl::Egfr^λ.UAS

(Chen et al., 2019)

Rok^JF03225, Scer\GAL4^GMR.PU is a suppressor of eye phenotype of Cln3^UAS.cTa, Scer\GAL4^GMR.PU

(Llavero Hurtado et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

The small eye induced by the expression of Cln3^UAS.cTa under the control of Scer\GAL4^GMR.PU is fully suppressed by the co-expression of Rok^JF03225.

(Llavero Hurtado et al., 2017)

Expression of Rok^JF03225 under the control of Scer\GAL4^GMR.PU enhances the rhabdomere fusion seen in eys¹ prom¹ double heterozygotes.

(Nie et al., 2014)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

28797

y¹ v¹; P{TRiP.JF03225}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Rok^JF03225

Rok^RNAi

(di Pietro et al., 2023)

rok^JF03225

Name Synonyms

Secondary FlyBase IDs

References (10)

Report Sections

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