FB2025_01 , released February 20, 2025
Allele: Dmel\ykiUAS.cOa.Tag:V5
Open Close
General Information
Symbol
Dmel\ykiUAS.cOa.Tag:V5
Species
D. melanogaster
Name
FlyBase ID
FBal0239732
Feature type
allele
Associated gene
Dmel\yki
Associated Insertion(s)
Carried in Construct
P{UAS-yki.V5.O}
Also Known As
UAS-Yki:V5, UAS-yki-V5, UAS-yki, UAS-yki.V5, Yki:V5, UAS-ykiWT, Yki-V5
Key Links
Transgenic product class
wild_type
(Oh and Irvine, 2009)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Oh and Irvine, 2009)
Mutagen
in vitro construct
(Oh and Irvine, 2009)
Progenitor genotype
Carried in construct
P{UAS-yki.V5.O}
Cytology
Description

UAS regulatory sequences drive expression of wild-type yki which is tagged with Tag:V5.

(Oh and Irvine, 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
yki
Tagged with
Tag:V5
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  carcinoma
      CEA with l(2)gl4
      (Enzo et al., 2015)
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  Alzheimer's disease 1
      modeled by Hsap\APPAβ42.UAS.cUa
      (Irwin et al., 2020)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expressing ykiUAS.cOa.Tag:V5 under the control of Scer\GAL4ptc-559.1 has no effect on the size of the anterior-posterior compartment boundary of the wing disc in third instar larvae.

      (Mach et al., 2018)

      The expression of ykiScer\UAS.cOa.T:SV5\V5 under the control of Scer\GAL4rn-GAL4, in combination with gal80[ts] to induce expression for 20h in third instar larvae, results in wing discs with hyperplasia but without epithelial cell polarity defects, as compared to controls.

      (Harris et al., 2016)

      Expressing ykiUAS.cOa.Tag:V5 under the control of Scer\GAL4insc-Mz1407 results in a significant increase in volume in the central nervous system of third instar larvae.

      (Poon et al., 2016)

      Expression of ykiScer\UAS.cOa.T:SV5\V5 under the control of Scer\GAL4GMR.PFa results in overgrowth of the eye, as compared to controls.

      (Sorrentino et al., 2014)

      Expression of ykiScer\UAS.cOa.T:SV5\V5 under the control of Scer\GAL4GMR.PFa does not result in larval eye disc overgrowth.

      (Gilbert et al., 2011)

      Expression of ykiScer\UAS.cOa.T:SV5\V5 under the control of Scer\GAL4repo.PU has no effect on glial cell number in third instar larval eye discs.

      (Reddy and Irvine, 2011)

      Expression of ykiScer\UAS.cOa.T:SV5\V5 under the control of Scer\GAL4sd-SG29.1 does not result in an evident mutant phenotype in the wing.

      Expression of ykiScer\UAS.cOa.T:SV5\V5 under the control of Scer\GAL4GMR.PF does not result in an evident mutant phenotype in the eye.

      Clones in the wing disc expressing ykiScer\UAS.cOa.T:SV5\V5 under the control of Scer\GAL4Act5C.PI have wild-type size and shape.

      (Oh and Irvine, 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Enhancer of
      Suppressor of
      NOT Suppressor of
      Other
      Phenotype Manifest In
      Suppressed by
      Enhancer of
      Suppressor of
      Statement
      Reference

      ykiUAS.cOa.Tag:V5, Scer\GAL4en.PU is a suppressor of wing phenotype of PatroninGD11946, Scer\GAL4en.PU

      (Yang and Choi, 2021)
      NOT Suppressor of
      Statement
      Reference

      ykiUAS.cOa.Tag:V5, Scer\GAL4en.PU is a non-suppressor of wing disc | larval stage phenotype of Klp10AUAS.cYa, Scer\GAL4en.PU

      (Yang and Choi, 2021)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of PfkHMS01324 suppresses the tumorigenic overgrowth seen in l(2)gl4 mutant wing discs expressing ykiScer\UAS.cOa.T:SV5\V5 under the control of Scer\GAL4tub.PU.

      (Enzo et al., 2015)

      Co-expression of βggt-IHMS01165 suppresses the eye overgrowth seen in flies expressing ykiScer\UAS.cOa.T:SV5\V5 under the control of Scer\GAL4GMR.PFa.

      (Sorrentino et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      ykiUAS.cOa.Tag:V5/Scer\GAL4ci.PC rescues ykiB5

      (Oh and Irvine, 2009)

      ykiUAS.cOa.Tag:V5/Scer\GAL4arm.PS rescues ykiB5

      (Oh and Irvine, 2009)
      Comments

      Expression of ykiScer\UAS.cOa.T:SV5\V5 under the control of Scer\GAL4ci.PC rescues the growth of ykiB5 clones in the wing disc.

      (Oh and Irvine, 2009)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ykiScer\UAS.cOa.T:SV5\V5
      ykiUAS.cOa.Tag:V5
      Name Synonyms
      Secondary FlyBase IDs
        References (26)