Amino acid replacement: S168A.
Amino acid replacement: S250A.
Expression of ykiS168A.S250A.Scer\UAS.T:SV5\V5 under the control of Scer\GAL4GMR.PF results in a greatly enlarged and folded eye, and viability is reduced.
Expression of ykiS168A.S250A.Scer\UAS.T:SV5\V5 under the control of Scer\GAL4sd-SG29.1 results in an extended third instar larval stage and eventual late larval lethality.
Co-expression of ykiS168A.S250A.Scer\UAS.T:SV5\V5 and hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.PF results in flies with greatly enlarged eyes (but less so than in the absence of hpoScer\UAS.T:Zzzz\FLAG).
Co-expression of ykiS168A.S250A.Scer\UAS.T:SV5\V5, wtsScer\UAS.T:Hsap\MYC and hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.PF results in flies with greatly enlarged eyes (but less so than in the absence of wtsScer\UAS.T:Hsap\MYC and hpoScer\UAS.T:Zzzz\FLAG).