Allele Dmel\Cyp4d21⁶⁷

General Information
Symbol	Dmel\Cyp4d21⁶⁷	Species	D. melanogaster
Name		FlyBase ID	FBal0239871
Feature type	allele	Associated gene	Dmel\Cyp4d21

Allele class	loss of function allele
Mutagen	FLPase, recombination, SCEI endonuclease, gene targeting by homologous recombination
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class	loss of function allele (Fujii et al., 2008)
Mutagen	FLPase (Fujii et al., 2008) gene targeting by homologous recombination (Fujii et al., 2008) recombination (Fujii et al., 2008) SCEI endonuclease (Fujii et al., 2008)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	P{FRT(Cyp4d21^{Scer\SceI.RS.cFa})} (Fujii et al., 2008)
Nature of the lesion	Statement Reference Homologous recombination at the Cyp4d21 locus, using P{FRT(Cyp4d21[Scer\SceI.RS.cFa])} as the donor template, has resulted in a mutation in which the 58bp region starting at position -5 (relative to the translational start site) has been replaced with a w marker. (Fujii et al., 2008)
Cytology
Phenotypic Data
Phenotypic Class
	mating defective \| male \| recessive (Fujii et al., 2008) viable (Fujii et al., 2008)
Phenotype Manifest In

Detailed Description
	Statement Reference Homozygous mutant males have a normal courtship index, but there is a significant increase in the fraction of homozygous males that do not mate compared to control males. Locomotion, taste preference, longevity and viability are normal in homozygous males. (Fujii et al., 2008)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescued by	Cyp4d21⁶⁷ is rescued by Cyp4d21^+tFa (Fujii et al., 2008)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Cyp4d21⁶⁷ sxe1⁶⁷ (Fujii et al., 2008)
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Fujii et al., 2008, Genetics 180(1): 179--190 A male-specific fatty acid omega-hydroxylase, SXE1, is necessary for efficient male mating in Drosophila melanogaster. [FBrf0207358]

Allele Dmel\Cyp4d2167

Allele Dmel\Cyp4d21⁶⁷