FB2025_05 , released December 11, 2025
Allele: Dmel\inaDsu100
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General Information
Symbol
Dmel\inaDsu100
Species
D. melanogaster
Name
FlyBase ID
FBal0239880
Feature type
allele
Associated gene
Dmel\inaD
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Georgiev et al., 2005)
Progenitor genotype
Cytology
Description

Mutation (CAG to TAG) introducing a stop codon just after the first PDZ domain.

(Georgiev et al., 2005)

Nucleotide substitution: C?T.

(Georgiev et al., 2005)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      inaDsu100 is a suppressor of visible phenotype of rdgA1

      (Georgiev et al., 2005)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      inaDsu100 is a suppressor of eye phenotype of rdgA1

      (Georgiev et al., 2005)

      inaDsu100/inaDT1 is a suppressor of rhabdomere phenotype of rdgA1

      (Georgiev et al., 2005)
      NOT Suppressor of
      Statement
      Reference

      inaDsu100 is a non-suppressor of rhabdomere phenotype of trpP365

      (Georgiev et al., 2005)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The retinal degeneration phenotype of rdgA1 flies is suppressed if the eyes are also composed entirely of homozygous inaDsu100 tissue (clones generated using the EGUF method).

      The retinal degeneration phenotype of trpP365 flies is not rescued by inaDsu100.

      The retinal degeneration phenotype of rdgA1 flies is suppressed by inaDT1/inaDsu100.

      (Georgiev et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      inaDsu100 is rescued by inaDGMR.PT

      (Georgiev et al., 2005)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: A mutation that suppresses the retinal degeneration phenotype of rdgA1 when the adult eye is composed entirely of homozygous mutant tissue (generated using the EGUF method).

      (Georgiev et al., 2005)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      inaDsu100
      su(100)
      (Georgiev et al., 2005)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)