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General Information
Symbol
Dmel\sdGA.UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0239888
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Sd-GA
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Tagged with Tag:HA.

UAS regulatory sequences drive expression of a constitutively active form of sd, in which sd is fused to the Scer\GAL4 activation domain.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expressing sdGA.UAS.Tag:HA under the control of Scer\GAL4ptc-559.1 stimulates tissue overgrowth in the wing disc, impairs wing pouch formation and results in a significant expansion of the ptc-positive anterior-posterior compartment boundary of the wing disc in third instar larvae.

An increased number of intestinal stem cells (ISCs) and enteroblasts are seen in the posterior midguts of adult flies expressing sdGA.Scer\UAS.T:Scer\GAL4-GAD.T:Ivir\HA1 under the control of Scer\GAL4esg-NP5130. The number of mitotic cells is also increased but intestinal hyperplasia is not seen.

Expression of sdGA.Scer\UAS.T:Scer\GAL4-GAD under the control of Scer\GAL4GMR.PF results in an overgrown eye phenotype.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of brmGD4507 greatly suppresses the intestinal stem cell overproliferation seen when sdGA.Scer\UAS.T:Scer\GAL4-GAD.T:Ivir\HA1 is expressed in adult flies under the control of Scer\GAL4esg-NP5130.

The overgrown eye phenotype caused by expression of sdGA.Scer\UAS.T:Scer\GAL4-GAD under the control of Scer\GAL4GMR.PF is not suppressed by hpoN.Scer\UAS.T:Zzzz\FLAG.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
sdGA.Scer\UAS.T:Scer\GAL4-GAD.T:Ivir\HA1
sdGA.Scer\UAS.T:Scer\GAL4-GAD
sdGA.UAS.Tag:HA
Name Synonyms
Secondary FlyBase IDs
    References (6)