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General Information
Symbol
Dmel\nopoExc142
Species
D. melanogaster
Name
FlyBase ID
FBal0239901
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
deletion
Comment:

Imprecise excision of P{EP}nopoG5845, resulting in a 771bp deletion that lacks part of the 5' UTR and exons encoding amino acid residues 1-181.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Imprecise excision of the progenitor insertion, resulting in a 771bp deletion that lacks part of the 5' UTR and exons encoding amino acid residues 1-181.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Embryos derived from nopoExc142 females fail to hatch. 94% of the embryos have abnormal spindle morphology.

15% of embryos derived from homozygous females mated to wild-type males develop to cycle 10 or beyond, but none of these embryos develop to the initiation of gastrulation or beyond.

7% of embryos derived from nopoExc142/Df(2R)Exel7153 females mated to wild-type males develop to cycle 10 or beyond, but none of these embryos develop to the initiation of gastrulation or beyond.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Statement
Reference
Suppressor of
Other
Statement
Reference

lokp6, nopoExc142/nopoZ1447 has interphase & organism | embryonic cycle 11 | maternal effect phenotype

Additional Comments
Genetic Interactions
Statement
Reference

Embryos derived from lokp6 nopoZ1447/lokp6 nopoExc142 females have significantly shorter interphases during cycle 11 compared to wild-type or lokp6 single mutant embryos.

Xenogenetic Interactions
Statement
Reference

Hsap\TRAIPnopo.PW rescues the hatch rate of embryos derived from nopoExc142 females from 0% to 83%, and the frequency of embryos with abnormal spindle morphology is reduced from 94% to 14%.

Complementation and Rescue Data
Rescued by
Partially rescued by

nopoExc142 is partially rescued by nopocDNA

Comments

nopocDNA rescues the hatch rate of embryos derived from nopoExc142 females from 0% to 76%, and the frequency of embryos with abnormal spindle morphology is reduced from 94% to 22%..

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (4)