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General Information
Symbol
Dmel\Traf4dsRNA.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0239950
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-dTRAF1-IR
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive Traf4 coding sequences in an inverted repeat to allow cell-targeted generation of dsRNA for RNAi knockdown experiments.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement
Reference
NOT Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The eye phenotype in Ras85DKP mutant flies is partially suppressed by ectopic expression of Traf4dsRNA.Scer\UAS in the eye under the control of Scer\GAL4GMR.PF.

The small-eye phenotype caused by expression of egrScer\UAS.cIa under the control of Scer\GAL4GMR.PF is not suppressed by co-expression of Traf4dsRNA.Scer\UAS.

Expression of Traf4dsRNA.Scer\UAS (under the control of Scer\GAL4Act5C.PI) using the FLP/FRT system fails to suppress metastatic behaviour in l(2)gl4 mutants expressing Ras85DV12.Scer\UAS.

Xenogenetic Interactions
Statement
Reference

Expression of Traf4dsRNA.Scer\UAS under the control of Scer\GAL4 in flies expressing BacA\p35GMR.PH does not result in an eye phenotype.

Expression of Traf4dsRNA.Scer\UAS (under the control of Scer\GAL4GMR.PF) and BacA\p35GMR.PH in a Ras85DKP mutant background strongly suppresses the eye phenotype.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Traf4dsRNA.Scer\UAS
Traf4dsRNA.UAS
Name Synonyms
Secondary FlyBase IDs
    References (5)