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General Information
Symbol
Dmel\Dlip31
Species
D. melanogaster
Name
FlyBase ID
FBal0240200
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Dip31
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
deletion
Comment:

930 bp deletion resulting from the imprecise excision of P{EP}Dip3C00008

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Imprecise excision of the progenitor insertion, resulting in a deletion that removes sequences from -21 to +909bp relative to the Dip3 transcription start site.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Ommatidia sometimes contain an extra rhabdomere and attached cell body located next to photoreceptor R7 in mutant adults. Almost 100% of mutant pupal ommatidia contain an extra photoreceptor (assayed by elav staining). The nucleus of one photoreceptor (most likely R7) is pushed towards the centre of the ommatidium in these pupal ommatidia.

In pupae containing homozygous clones in the eye, all mosaic ommatidia containing four or more wild-type photoreceptors have the normal number of eight photoreceptors, while all mosaic ommatidia containing fewer than four wild-type photoreceptors have an extra photoreceptor. There is no discernible pattern in the arrangement of wild-type photoreceptors within the ommatidia that contain an extra photoreceptor.

7% of Dip31 mutant embryos fail to hatch and exhibit D/V patterning defects.

Dip31 mutants show 55% lethality one month after bacterial infection with a 1:1 mixture of M. luteus (Gram-positive) and E. coli (Gram-negative), compared to 10% in wild-type. Wild-type and Dip31 mutant adults are equally sensitive to fungal infection (B. brassiana), with both showing 55-70% lethality after 30 days. Dip31 mutant larvae show a reduced eclosion rate following injection with M. luteus and E. coli.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

An increased proportion of embryos maternally mutant for Dip31 and dl1/+ show D\V patterning defects compared to dl1/+ alone. Loss of paternal Dip3 has no effect on the dl1/+ phenotype.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)