FB2025_04 , released October 2, 2025
Allele: Dmel\taiHM05182
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General Information
Symbol
Dmel\taiHM05182
Species
D. melanogaster
Name
FlyBase ID
FBal0240311
Feature type
allele
Associated gene
Dmel\tai
Associated Insertion(s)
Carried in Construct
P{TRiP.HM05182}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
in vitro construct
(Perkins et al., 2009)
Progenitor genotype
Carried in construct
P{TRiP.HM05182}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-HM05182
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of taiHM05182 under the control of Scer\GAL4en.PU in third instar larvae leads to shrinkage of the posterior domain of the wing disc without significantly altering the size of the anterior domain, as compared to controls. These flies die during P-stage.

      Expression of taiHM05182 under the control of Scer\GAL4Bx-MS1096 results in a significant reduction in wing size, as compared to wild type.

      Expression of taiHM05182 under the control of Scer\GAL4GMR.PU shrinks both adult head and eye size, as compared to wild type.

      (Zhang et al., 2015)

      The expression of taiHM05182 under the control of Scer\GAL4221 results in a reduced dendritic arborization in third instar larval class I abdominal dorsal multidendritic ddaD and ddaE neurons, as compared to controls; expression under the control of Scer\GAL4ppk.PG, in combination with Dicer-2 for efficient RNAi, results in no obvious dendrite morphology defects in abdominal dorsal multidendritic ddaD neurons, as compared to controls.

      (Hattori et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      taiHM05182/Scer\GAL4GMR.PU is a suppressor of eye phenotype of Scer\GAL4GMR.PU, ykiS168A.UAS.YFP

      (Zhang et al., 2015)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of taiHM05182 leads to low adult survival, but shrinks both adult head and eye size in flies expressing ykiS168A.Scer\UAS.T:Avic\GFP-YFP under the control of Scer\GAL4GMR.PU.

      (Zhang et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      taiHM05182
      Name Synonyms
      Secondary FlyBase IDs
        References (6)