FB2025_01 , released February 20, 2025
Allele: Dmel\SkpAHM05185
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General Information
Symbol
Dmel\SkpAHM05185
Species
D. melanogaster
Name
FlyBase ID
FBal0240314
Feature type
allele
Associated gene
Dmel\SkpA
Associated Insertion(s)
Carried in Construct
P{TRiP.HM05185}
Also Known As
UAS-skpARNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
in vitro construct
(Perkins et al., 2009)
Progenitor genotype
Carried in construct
P{TRiP.HM05185}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-HM05185
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies carrying clones expressing SkpAHM05185 under the control of Scer\GAL4Act.PU in the Johnston's organ display detached scolopidia phenotype.

      (Li et al., 2016)

      Expression of SkpAHM05185 in the fat body under the control of Scer\GAL4DcG results in significant hyperglycaemia.

      (Ugrankar et al., 2015)

      Scer\GAL4sd.PU-mediated expression of SkpAHM05185 substantially reduces wing size.

      Scer\GAL4sd.PU- or Scer\GAL4en.PU-mediated expression of SkpAHM05185 strongly induces cell death in wing discs.

      (Fereres et al., 2013)

      Expression of skpAHM05185 under the control of Scer\GAL4ppk.PG produces dendrite pruning defects in ddaC neurons at 16 hours after puparium formation. No difference is seen at the white prepupal stage.

      (Wong et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Suppressed by
      Enhancer of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Scer\GAL4sd.PU-mediated expression of both SkpAHM05185 and RYBPdsRNA.Scer\UAS.cGa reduces wing size to a greater extent than expression of either transgene alone.

      Scer\GAL4en.PU-mediated expression of both SkpAHM05185 and RYBPdsRNA.Scer\UAS.cGa increases cell death in the wing disc to a greater extent than expression of either transgene alone.

      Co-expression of rprGD4698 or Diap1Scer\UAS.cUa strongly reduces the cell death induced in wing discs by Scer\GAL4sd.PU-mediated expression of SkpAHM05185.

      (Fereres et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      SkpAHM05185
      skpAHM05185
      Name Synonyms
      Secondary FlyBase IDs
        References (9)