FlyBase Allele Report: Dmel\shf[UAS.cGb]

General Information

Symbol

Dmel\shf^UAS.cGb

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct of Glise

FlyBase ID

FBal0240339

Feature type

allele

Associated gene

Dmel\shf

Associated Insertion(s)

Carried in Construct

P{UAS-shf.Gb}

Also Known As

UAS-shf

Key Links

Transgenic product class

cDNA

(Glise et al., 2005)

wild_type

(Glise et al., 2005)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Glise et al., 2005)

wild_type

(Glise et al., 2005)

Mutagen

in vitro construct

(Glise et al., 2005)

Progenitor genotype

Carried in construct

P{UAS-shf.Gb}

Cytology

Description

Expression of shf cDNA (GH27042) is under the control of UAS sequences.

(Glise et al., 2005)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

shf

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

shf^UAS.cGb, Scer\GAL4^nub-AC-62 is a suppressor | partially of wing phenotype of Drer\wif1^UAS.cAa, Scer\GAL4^nub-AC-62

(Avanesov et al., 2012)

shf^UAS.cGb, Scer\GAL4^nub-AC-62 is a suppressor | partially of wing margin bristle phenotype of Drer\wif1^UAS.cAa, Scer\GAL4^nub-AC-62

(Avanesov et al., 2012)

shf^UAS.cGb/Scer\GAL4^nub-AC-62 is a suppressor | partially of wing phenotype of Scer\GAL4^nub-AC-62, fz2^{GPI.UAS.Tag:MYC}

(Avanesov et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Expression of shf^Scer\UAS.cGb partially suppresses the adult wing defects seen when Drer\wif1^Scer\UAS.cAa is expressed under the control of Scer\GAL4^nub-AC-62. The amount of wing margin notching is reduced and the first longitudinal vein and some anterior bristles are restored.

Expression of shf^Scer\UAS.cGb partially suppresses the adult wing margin defects seen when fz2^{GPI.Scer\UAS.T:Hsap\MYC} is expressed under the control of Scer\GAL4^nub-AC-62.

(Avanesov et al., 2012)

Complementation and Rescue Data

Rescues

shf^UAS.cGb/Scer\GAL4^Bx-MS1096 rescues shf²

(Glise et al., 2005)

Scer\GAL4^en-e16E/shf^UAS.cGb rescues shf²

(Glise et al., 2005)

shf^UAS.cGb/Scer\GAL4^dpp.blk1 rescues shf²

(Glise et al., 2005)

Scer\GAL4^ptc-559.1/shf^UAS.cGb rescues shf²

(Glise et al., 2005)

shf^UAS.cGb/Scer\GAL4^ap-md544 rescues shf²