Open Close
General Information
Symbol
Dmel\CragCJ101
Species
D. melanogaster
Name
FlyBase ID
FBal0240375
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

C8595010T

Amino acid change:

Q367term | Crag-PA; Q367term | Crag-PB; Q367term | Crag-PD

Reported amino acid change:

Q367term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: Q367term.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Electroretinogram (ERG) responses of flies containing homozygous clones in the eye are normal for 1 and 14 day old flies kept in constant darkness. However, if the flies are reared under 12 hour light/12 hour dark conditions, both the amplitude of the ERG and the size of the "on" and "off" transients become smaller with age. If the flies are kept under constant light conditions, the ERG amplitude is severely affected, showing a 90% reduction after only 5 days.

Homozygous follicle cell clones at the poles of the egg chamber are irregular in shape and pile up in multiple layers. In many cases, these multilayered regions comprise a mixture of mutant and wild-type cells. Homozygous follicle cell clones on the lateral sides of the egg chamber are indistinguishable from wild type.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (5)