Open Close
General Information
Symbol
Dmel\rprGMR.PU
Species
D. melanogaster
Name
glass multimer reporter construct of Unknown
FlyBase ID
FBal0240692
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
GMR-rpr
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

GMR regulatory sequences drive expression of rpr.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

rprGMR.PU leads to small eyes with apoptotic phenotypes in the retina.

Expression of rprGMR.PU results in small and rough eye phenotype in adult flies.

Expression of rprGMR.PU results in a reduced eye size compared to controls and severe disruption to the ommatidia.

Ectopic expression of one copy of rprGMR.PU under the control of Scer\GAL4GMR.PU in flies causes eye ablation.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhanced by
Statement
Reference

rprGMR.PU has visible phenotype, non-enhanceable by ecEPΔ4

rprGMR.PU has visible phenotype, non-enhanceable by ecSF1.GMR

Suppressed by
NOT suppressed by
Statement
Reference

rprGMR.PU has visible phenotype, non-suppressible by ecEPΔ4

rprGMR.PU has visible phenotype, non-suppressible by ecSF1.GMR

Phenotype Manifest In
NOT Enhanced by
Statement
Reference

rprGMR.PU has eye phenotype, non-enhanceable by ecEPΔ4

rprGMR.PU has eye phenotype, non-enhanceable by ecSF1.GMR

Suppressed by
NOT suppressed by
Statement
Reference

rprGMR.PU has eye phenotype, non-suppressible by ecEPΔ4

rprGMR.PU has eye phenotype, non-suppressible by ecSF1.GMR

Additional Comments
Genetic Interactions
Statement
Reference

Expression of DCAF12GD10933 driven by Scer\GAL4GMR.PU partially suppresses apoptotic eye phenotypes in rprGMR.PU flies.

The strongly reduced eye size characteristic for adult flies expressing rprGMR.PU is partially reverted by expression of either DubaGD11813 or DubaKK108478 under the control of Scer\GAL4GMR.PU or by combination with the Duba107 allele in heterozygous state.

Eye cell death observed in rprGMR.PU flies is suppressed by expression of Den1VDRC.cUa under the control of Scer\GAL4GMR.PF.

Eye cell death observed in rprGMR.PU flies is suppressed by expression of CSN5NIG.14884R under the control of Scer\GAL4GMR.PF.

Eye cell death observed in rprGMR.PU flies is suppressed by expression of CG1503VDRC.cUa under the control of Scer\GAL4GMR.PF.

Eye cell death observed in rprGMR.PU flies is suppressed in a Den1EX9 mutant background.

Xenogenetic Interactions
Statement
Reference

Expression of Hsap\LRRK2Scer\UAS.cCa under the control of Scer\GAL4GMR.PU partially suppresses the eye phenotypes seen upon expression of rprGMR.PU.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
rprGMR.PU
Name Synonyms
glass multimer reporter construct of Unknown
Secondary FlyBase IDs
    References (7)