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General Information
Symbol
Dmel\ApplJF02878
Species
D. melanogaster
Name
FlyBase ID
FBal0240847
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UAS regulatory sequences drive expression of an inverted repeat.
Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Adult flies expressing ApplJF02878 under the control of Scer\GAL4GMR.PF display eye morphology defects of varying severity (from mild glossy appearance with no size reduction ranging to very small glossy eyes with highly degenerated ommatidia and bristle loss). Expression under the Scer\GAL4elav-C155 driver leads to age-progressive decrease of locomotor (climbing) ability and shorter lifespan.
Expression of ApplJF02878 in the eye under the control of Scer\GAL4hs.2sev results in loss of photoreceptors and planar cell polarity (PCP)-like phenotypes characterised by the presence of R3-R3 symmetrical clusters.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Phenotype Manifest In
Enhanced by
Additional Comments
Genetic Interactions
Statement
Reference
Co-expression of hbsVDRC.cUa with ApplJF02878 under the control of Scer\GAL4hs.2sev significantly enhances the hbsVDRC.cUa-induce planar cell polarity (PCP) phenotype.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
ApplJF02878
Name Synonyms
Secondary FlyBase IDs
    References (4)