Adult flies expressing ApplJF02878
under the control of Scer\GAL4GMR.PF
display eye morphology defects of varying severity (from mild glossy appearance with no size reduction ranging to very small glossy eyes with highly degenerated ommatidia and bristle loss). Expression under the Scer\GAL4elav-C155
driver leads to age-progressive decrease of locomotor (climbing) ability and shorter lifespan.
Expression of ApplJF02878
in the eye under the control of Scer\GAL4hs.2sev
results in loss of photoreceptors and planar cell polarity (PCP)-like phenotypes characterised by the presence of R3-R3 symmetrical clusters.