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General Information
Symbol
Dmel\Nhe21
Species
D. melanogaster
Name
FlyBase ID
FBal0241142
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
deletion
Comment:

Estimated endpoints of 6.1kb deletion resulting from the imprecise excision of P{EPgy2}Nhe2EY11323, which removes the promoters and 5' untranslated exons of Nhe2 . One breakpoint is at the insertion site and the other is 6.1 kb upstream.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference

Imprecise excision of the progenitor insertion, resulting in a 6.1kb deletion.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygotes die during early larval stages with defects in gut morphology and function and fat body development.

Homozygous clones can not be recovered in adult or larval tissue.

Expression of Nhe2dsRNA.Scer\UAS.WIZ under the control of Scer\GAL4hs.2sev in a Nhe21/+ background results in planar cell polarity defects in the eye, as well as general defects in eye morphology and structure.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Phenotype Manifest In
Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The planar cell polarity defects in the eye that are caused by expression of fzScer\UAS.cAa under the control of Scer\GAL4hs.2sev are partially suppressed if the flies also simultaneously co-express Nhe2dsRNA.Scer\UAS.WIZ and carry Nhe21/+.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (1)