Allele Dmel\lft^NIG.13139R

General Information
Symbol	Dmel\lft^NIG.13139R	Species	D. melanogaster
Name		FlyBase ID	FBal0241156
Feature type	allele	Associated gene	Dmel\lft

Map ( GBrowse )
Allele class
Mutagen	in vitro construct - RNAi, in vitro construct - regulatory fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Mao et al., 2009) in vitro construct - RNAi (Mao et al., 2009)
Mutations Mapped to the Genome

Type Location Additional Notes References RNAi reagent :1..71 :72..235 :236..426 :427..500
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS regulatory sequences drive expression of a hairpin of lft sequences. (Mao et al., 2009)
Carried in construct	P{NIG.13139R} (Mao et al., 2009)
Associated Sequence Features	dsRNA-13139R
Cytology
Phenotypic Data
Phenotypic Class
	visible, with Scer\GAL4^Act.PU (Mao et al., 2009)
Phenotype Manifest In
	wing, with Scer\GAL4^Act.PU (Mao et al., 2009) wing disc \| posterior compartment, with Scer\GAL4^en-e16E (Mao et al., 2009)
Detailed Description
	Statement Reference Expression of lft[NIG.13139R] under the control of Scer\GAL4[Act] results in flies with slightly shorter wings than normal. The reduced length of the wing is most obvious in the middle of the wing, where the distance between the anterior and the posterior crossveins is decreased. Expression of lft[NIG.13139R] under the control of Scer\GAL4[en-e16E] results in a modest, but statistically significant, increase in the relative size of the posterior compartment of the wing disc (where Scer\GAL4[en-e16E] is expressed) to 87% of anterior compartment size (in control wing discs, the posterior compartment is 80% of the size of the anterior compartment). (Mao et al., 2009)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference Co-expression of lft[NIG.13139R] enhances the overgrowth of the the posterior compartment of the wing disc that is seen in animals expressing ds[GD14350] under the control of Scer\GAL4[en-e16E], such that the posterior compartment is 178% of anterior compartment size (in control wing discs, the posterior compartment is 80% of the size of the anterior compartment). (Mao et al., 2009)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	lft^NIG.13139R
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Mao et al., 2009, Development 136(19): 3223--3233 Drosophila lowfat, a novel modulator of Fat signaling. [FBrf0209094]

Allele Dmel\lftNIG.13139R

Allele Dmel\lft^NIG.13139R