FB2025_01 , released February 20, 2025
Allele: Dmel\tutlΔcyto.UAS
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General Information
Symbol
Dmel\tutlΔcyto.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0241230
Feature type
allele
Associated gene
Dmel\tutl
Associated Insertion(s)
Carried in Construct
P{UAS-tutl.Δcyto}
Key Links
Transgenic product class
inframe_deletion
(Long et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Long et al., 2009)
Mutagen
in vitro construct
(Long et al., 2009)
Progenitor genotype
Carried in construct
P{UAS-tutl.Δcyto}
Cytology
Description

UASt regulatory sequences drive expression of a truncated tutl protein (amino acids residues 1-879 predicted by the tutl-RD isoform).

(Long et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
tutl
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      tutlΔcyto.UAS/Scer\GAL4221 rescues tutl01085/tutl23

      (Long et al., 2009)
      Partially rescues

      Scer\GAL4elav-C155/tutlΔcyto.UAS partially rescues tutl01085/tutl23

      (Long et al., 2009)
      Comments

      Expression of tutlΔcyto.Scer\UAS under the control of Scer\GAL4221 restores the number of dendrite branch termini per cell to wild-type levels in tutl01085/tutl23 ddaE neurons.

      Expression of tutlΔcyto.Scer\UAS under the control of Scer\GAL4elav-C155 rescues the viability of tutl01085/tutl23 mutants to 20%.

      (Long et al., 2009)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      tutlΔcyto.Scer\UAS
      tutlΔcyto.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)