Allele Dmel\W^Scer\UAS.cHa

General Information
Symbol	Dmel\W^Scer\UAS.cHa	Species	D. melanogaster
Name	Saccharomyces cerevisiae UAS construct a of Hafen	FlyBase ID	FBal0241231
Feature type	allele	Associated gene	Dmel\W

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Buch et al., 2008)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS regulatory sequences drive expression of W. (Buch et al., 2008)
Carried in construct	P{UAS-hid.H} (Buch et al., 2008)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Other
Statement Reference Scer\GAL4^Ilp3.PB, W^Scer\UAS.cHa, rpr^Scer\UAS.C has long lived phenotype (Buch et al., 2008)
Phenotype Manifest In
Other
Statement Reference Scer\GAL4^Ilp3.PB, W^Scer\UAS.cHa, rpr^Scer\UAS.C has neurosecretory neuron phenotype (Buch et al., 2008)
Additional Comments
Genetic Interactions
Statement Reference Co-expression of W[Scer\UAS.cHa] and rpr[Scer\UAS.C] under the control of Scer\GAL4[Ilp3.PB] ablates all of the insulin-producing cells (IPCs) specifically at the postlarval stage (larval IPCs are not ablated). Flies co-expressing W[Scer\UAS.cHa] and rpr[Scer\UAS.C] under the control of Scer\GAL4[Ilp3.PB] and raised on fly maintenance food show no change in longevity compared to wild-type controls. Flies co-expressing W[Scer\UAS.cHa] and rpr[Scer\UAS.C] under the control of Scer\GAL4[Ilp3.PB] and raised on fly food with yeast paste show an increase in life span compared to wild-type controls. (Buch et al., 2008)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	W^Scer\UAS.cHa
Name Synonym	Saccharomyces cerevisiae UAS construct a of Hafen
Secondary FlyBase IDs

References ( 1 )
Research paper	Buch et al., 2008, Cell Metab. 7(4): 321--332 Opposing effects of dietary protein and sugar regulate a transcriptional target of Drosophila insulin-like peptide signaling. [FBrf0204261]

Allele Dmel\WScer\UAS.cHa

Allele Dmel\W^Scer\UAS.cHa