Allele Dmel\Npc1b^{Scer\SceI.RS.cVa}

General Information
Symbol	Dmel\Npc1b^{Scer\SceI.RS.cVa}	Species	D. melanogaster
Name		FlyBase ID	FBal0241343
Feature type	allele	Associated gene	Dmel\Npc1b

Allele class
Mutagen	in vitro construct
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct (Voght et al., 2007)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Contains a Npc1b genomic fragment (nucleotides 273721-280080 of GenBank accession AE003569) which has been modified to include a stop codon at amino acid position 392, several splice-site mutations, an XhoI diagnostic restriction site and an Scer\SceI.RS site. (Voght et al., 2007)
Carried in construct	P{FRT(Npc1b^{Scer\SceI.RS.cVa})} (Voght et al., 2007)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	Donor construct for gene targeting at the Npc1b locus. (Voght et al., 2007)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Npc1b^{Scer\SceI.RS.cVa}
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Voght et al., 2007, Cell Metab. 5(3): 195--205 Drosophila NPC1b promotes an early step in sterol absorption from the midgut epithelium. [FBrf0193836]

Allele Dmel\Npc1bScer\SceI.RS.cVa

Allele Dmel\Npc1b^{Scer\SceI.RS.cVa}