FB2025_01 , released February 20, 2025
Allele: Dmel\EloAG4930
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General Information
Symbol
Dmel\EloAG4930
Species
D. melanogaster
Name
FlyBase ID
FBal0241413
Feature type
allele
Associated gene
Dmel\EloA
Associated Insertion(s)
P{EP}EloAG4930
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(Rougeot et al., 2013)
Mutagen
P-element activity
(Bellen, 2010.2.4)
Progenitor genotype
Associated Insertion(s)
P{EP}EloAG4930
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes have normal wing veins.

      53.7% of females expressing EloAG4930 under the control of Scer\GAL4sd.PU have ectopic wing veins. Wing margin defects are also seen.

      85.5% of females expressing EloAG4930 under the control of Scer\GAL4Bx-MS1096 have ectopic wing veins.

      Clones expressing EloAG4930 under the control of Scer\GAL4Act5C.PP results in wing margin and wing vein defects.

      (Rougeot et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      EloA[+]/EloAG4930 is a suppressor | partially of visible | dominant phenotype of corto07128b

      (Rougeot et al., 2013)

      EloA[+]/EloAG4930 is a suppressor of visible | dominant phenotype of cortol1

      (Rougeot et al., 2013)

      EloA[+]/EloAG4930 is a suppressor of visible | dominant phenotype of kis1

      (Rougeot et al., 2013)

      EloA[+]/EloAG4930 is a suppressor of visible | dominant phenotype of mor1

      (Rougeot et al., 2013)

      EloA[+]/EloAG4930 is a suppressor of visible | dominant phenotype of trxE2

      (Rougeot et al., 2013)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      EloA[+]/EloAG4930 is a suppressor | partially of wing vein | ectopic phenotype of corto07128b

      (Rougeot et al., 2013)

      EloA[+]/EloAG4930 is a suppressor of wing vein | ectopic phenotype of cortol1

      (Rougeot et al., 2013)

      EloA[+]/EloAG4930 is a suppressor of wing vein | ectopic phenotype of kis1

      (Rougeot et al., 2013)

      EloA[+]/EloAG4930 is a suppressor of wing vein | ectopic phenotype of mor1

      (Rougeot et al., 2013)

      EloA[+]/EloAG4930 is a suppressor of wing vein | ectopic phenotype of trxE2

      (Rougeot et al., 2013)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The penetrance of the ectopic wing vein phenotype seen in corto07128b/+ females (over 90% penetrance) is reduced if they are also heterozygous for EloAG4930 (38.3% penetrance).

      The ectopic wing vein phenotype seen in cortol1/+ females is suppressed if they are also heterozygous for EloAG4930.

      The penetrance of the ectopic wing vein phenotype seen in mor1/+ females (22.5% penetrance) is reduced if they are also heterozygous for EloAG4930 (5.5% penetrance).

      The penetrance of the ectopic wing vein phenotype seen in kis1/+ females (81.5% penetrance) is reduced if they are also heterozygous for EloAG4930 (48.8% penetrance).

      The penetrance of the ectopic wing vein phenotype seen in trxE2/+ females (53.9% penetrance) is reduced if they are also heterozygous for EloAG4930 (10.4% penetrance).

      (Rougeot et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      EloAG4930
      (Rougeot et al., 2013, Bellen, 2010.2.4)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)