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General Information
Symbol
Dmel\larpS003108
Species
D. melanogaster
Name
FlyBase ID
FBal0241443
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{lacW} insertion in the first intron.

Insertion components
P{lacW}larpS003108
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

71% of larpS003108/larpmtr-null females are sterile.

Eggs laid by larpS003108/larpmtr-null females show a number of defects during syncytial divisions, including chains of linked spindles, free centrosomes, multipolar spindles, chromosome segregation defects and a loss of synchrony throughout the syncytial divisions.

35.4% of homozygous spermatocytes show defects in meiosis.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
Enhancer of
Statement
Reference
Other
Phenotype Manifest In
Enhanced by
Statement
Reference

larpS003108 has spermatocyte phenotype, enhanceable by pAbp[+]/pAbpEP310

Enhancer of
Statement
Reference

larpS003108/larp[+] is an enhancer of spermatocyte phenotype of pAbpEP310

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

16% of pAbpEP310/+ ; larpS003108/+ double heterozygous spermatocytes show defects in meiosis.

The frequency of homozygous pAbpEP310 spermatocytes that show defects in meiosis (17%) is increased by larpS003108/+ (to 29.3%).

The frequency of homozygous larpS003108 spermatocytes that show defects in meiosis (35.4%) is increased by pAbpEP310/+ (to 48%).

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Allelic series (severity of mutant alleles): larpmtr-null > larpS003108 > larpS022529 > larp06487.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (7)
Reported As
Symbol Synonym
l(3)S003108S003108
l(3)S003108l(3)S003108
larpS003108
larp<up>mtr w</up>
Name Synonyms
Secondary FlyBase IDs
  • FBal0220947
  • FBal0130100
References (3)