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General Information
Symbol
Dmel\larpS022529
Species
D. melanogaster
Name
FlyBase ID
FBal0241444
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{lacW} insertion in the first intron.

Insertion components
P{lacW}larpS022529
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

45% of larpS022529/larpmtr-null females are sterile.

Eggs laid by larpS022529/larpmtr-null females show a number of defects during syncytial divisions, including chains of linked spindles and free centrosomes. Time-lapse imaging shows that centrosomes can be seen to successfully duplicate following the previous division cycle, however the movement of the centrosomes around the nuclear membrane is hindered. Nonetheless, a spindle forms between the two groups of centrosomes. Nuclear spacing is also disrupted.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Allelic series (severity of mutant alleles): larpmtr-null > larpS003108 > larpS022529 > larp06487.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (6)
Reported As
Symbol Synonym
l(3)S022529S022529
larpS022529
larp<up>mtr 1</up>
Name Synonyms
Secondary FlyBase IDs
  • FBal0220946
  • FBal0130029
References (3)