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General Information
Symbol
Dmel\Axud1UAS.cGa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Glavic
FlyBase ID
FBal0241583
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of an Axud1 cDNA.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Scer\GAL4salm-EPv-driven expression of Axud1Scer\UAS.cGa in the central region of the wing (L2 to L4) produces a non-allometric reduction in size and the collapse of the L2-L3 intervein.

Eye size is reduced as a result of Scer\GAL4ey.PH-driven expression of Axud1Scer\UAS.cGa.

The number of cells in S-phase is severely reduced, while the number of mitotic cells is increased when Axud1Scer\UAS.cGa is ectopically expressed with Scer\GAL4salm-EPv in the larval wing imaginal disc.

Scer\GAL4MD-638-driven expression of Axud1Scer\UAS.cGa strongly impairs wing development.

Larval eye imaginal disc cells expressing Scer\GAL4GMR.PFa-driven Scer\GAL4[GMR.PFa] enter apoptosis as result of mitotic blockage.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
NOT Enhanced by
Statement
Reference
Suppressed by
NOT suppressed by
Statement
Reference
Other
Phenotype Manifest In
Enhanced by
Statement
Reference
NOT Enhanced by
Statement
Reference
Suppressed by
NOT suppressed by
Statement
Reference
Other
Additional Comments
Genetic Interactions
Statement
Reference

Expression of Axud1Scer\UAS.cGa with Scer\GAL4salm-EPv in a heterozygous pucE69 background significantly enhances the reduction in wing size.

Expression of Axud1Scer\UAS.cGa with Scer\GAL4salm-EPv in a heterozygous hepr75 background results in a partial suppression of the ectopic Axud1Scer\UAS.cGa expression wing phenotype.

Expression of Axud1Scer\UAS.cGa with Scer\GAL4salm-EPv in a heterozygous bskJ27 background results in a partial suppression of the ectopic Axud1Scer\UAS.cGa expression wing phenotype.

The wing impairment resulting from the ectopic expression of Scer\GAL4MD-638-driven Axud1Scer\UAS.cGa is suppressed by the co-expression of cdc2Scer\UAS.T:Hsap\MYC.

Xenogenetic Interactions
Statement
Reference

Scer\GAL4salm-EPv-driven co-expression of BacA\p35Scer\UAS.cHa with Axud1Scer\UAS.cGa produces epithelial extrusion in the adult wing.

The cell cycle abnormalities of the larval wing imaginal disc cells resulting from the Scer\GAL4salm-EPv-driven expression of Axud1Scer\UAS.cGa are not modified by the co-expression of BacA\p35Scer\UAS.cHa.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Axud1Scer\UAS.cGa
Axud1UAS.cGa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Glavic
Secondary FlyBase IDs
    References (1)