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General Information
Symbol
Dmel\sip3UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0241807
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Hrd1
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of sip3 which is tagged at the N-terminal end with Tag:MYC.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of sip3Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4ninaE.PT does not result in retinal degeneration (as determined using the pseudopupil assay).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The abnormal eye morphology resulting from the expression of ninaEG69D.GMR under the combined control of Scer\GAL4GMR.PU, Scer\GAL4ey.PU is suppressed by the co-expression of sip3Scer\UAS.T:Hsap\MYC alone, but not by co-expression of sip3Scer\UAS.T:Hsap\MYC in combination with sip3GD3145, CG32441KK104001, PnglKK101641, CG11070KK101530, asrijKK108914, CG2126GD3969, hiroKK101387 or CG6766GD5521 (in combination with Dicer-2, for efficient RNAi).

Expression of sip3Scer\UAS.T:Hsap\MYC or under the control of Scer\GAL4ninaE.PT dramatically decreases the rate of pseudopupil loss seen in ninaEG69D/+ flies. The ommatidial defects seen in 21 day old ninaEG69D/+ flies are also suppressed in the double mutants.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
sip3Scer\UAS.T:Hsap\MYC
sip3UAS.Tag:MYC
Name Synonyms
Secondary FlyBase IDs
    References (4)