FlyBase Allele Report: Dmel\SF2[HM05199]

FB2025_01 , released February 20, 2025

FB2025_01 , released February 20, 2025

Allele: Dmel\SF2^HM05199

General Information

Symbol

Dmel\SF2^HM05199

Species

D. melanogaster

Name

FlyBase ID

FBal0242118

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{TRiP.HM05199}

Key Links

Genomic Maps

Transgenic product class

(Perkins et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Perkins et al., 2009)

Mutagen

in vitro construct

(Perkins et al., 2009)

Progenitor genotype

Carried in construct

P{TRiP.HM05199}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Also carries

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates fragile X-associated tremor/ataxia syndrome

modeled by Zzzz\CGG^90.UAS.EGFP

(Linsalata et al., 2019)

ameliorates cancer

modeled by Pten^KK109278

(Parniewska and Stocker, 2020)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

SF2^HM05199, Scer\GAL4^GMR.PU is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4^GMR.PU, Zzzz\GGGGCC^30.UAS.EGFP

(Kankel et al., 2020)

SF2^HM05199, Scer\GAL4^GMR.PU is a suppressor of visible | adult stage phenotype of Hsap\TARDBP^{M337V.UAS.Tag:MYC}, Scer\GAL4^GMR.PU

(Kankel et al., 2020)

SF2^HM05199, Scer\GAL4^GMR.PU is a suppressor of visible | adult stage phenotype of Hsap\FUS^{R521C.UAS.Tag:HA}, Scer\GAL4^GMR.PU

(Kankel et al., 2020)

Phenotype Manifest In

Suppressor of

Statement

Reference

SF2^HM05199, Scer\GAL4^GMR.PU is a suppressor | partially of eye phenotype of Scer\GAL4^GMR.PU, Zzzz\GGGGCC^30.UAS.EGFP

(Kankel et al., 2020)

SF2^HM05199, Scer\GAL4^GMR.PU is a suppressor of eye phenotype of Hsap\TARDBP^{M337V.UAS.Tag:MYC}, Scer\GAL4^GMR.PU

(Kankel et al., 2020)

SF2^HM05199, Scer\GAL4^GMR.PU is a suppressor of eye phenotype of Hsap\FUS^{R521C.UAS.Tag:HA}, Scer\GAL4^GMR.PU

(Kankel et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

29522

y¹ v¹; P{TRiP.HM05199}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

SF2^HM05199

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections