FB2025_01 , released February 20, 2025
Allele: Dmel\CadNJF02653
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General Information
Symbol
Dmel\CadNJF02653
Species
D. melanogaster
Name
FlyBase ID
FBal0242242
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-NcadRNAi
Key Links
Genomic Maps

Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The expression of CadNJF02653 under the control of Scer\GAL4sev.PM181 leads to the larval medulla showing significantly disturbed columns and R7 photoreceptor axon terminals expanding toward the peripheral part of the column, but still innervating on the larval medulla neuropil, as compared with controls. as compared with controls; R8 photoreceptor and Mi1 neuron terminals also become disorganized, expanded and overlap R7 photoreceptor terminals.

The expression of CadNJF02653 under the control of Scer\GAL4sens.F2 leads to the larval medulla showing R8 photoreceptor terminals that are deformed and expanded to fuse with neighboring columns; R7 photoreceptor terminals also become expanded and enwrapped by R8 terminals; Mi1 neuron terminals also become expanded and overlap more with R8 photoreceptor terminals.

Clonal expression of CadNJF02653 under the control of Scer\GAL4GMR.PC in R7 photoreceptors (induced by Scer\FLP1G5.20C11) leads to axon terminals expanding toward the peripheral part of the column in the larval medulla, although the column morphology is largely preserved, as compared with controls.

Clonal expression of CadNJF02653 under the control of Scer\GAL4GMR.PC in R8 photoreceptors (induced by Scer\FLP1G5.sens.PC) leads to axon terminals expanding toward the peripheral part of the column in the larval medulla, as compared to controls.

Males expressing CadNJF02653 under the control of Scer\GAL4fru.P1.D show no appreciable courtship behaviour towards wild-type females during a 1 hour observation period.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
CadNJF02653
Name Synonyms
Secondary FlyBase IDs
    References (6)