FlyBase Allele Report: Dmel\Alk[JF02668]

General Information

Symbol

Dmel\Alk^JF02668

Species

D. melanogaster

Name

FlyBase ID

FBal0242257

Feature type

allele

Associated gene

Dmel\Alk

Associated Insertion(s)

Carried in Construct

P{TRiP.JF02668}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

(Perkins et al., 2009)

Progenitor genotype

Carried in construct

P{TRiP.JF02668}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-JF02668

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal developmental rate, with Scer\GAL4^phtm.PO

(Pan and O'Connor, 2021)

abnormal eclosion rhythm, with Scer\GAL4^phtm.PU

(Cavieres-Lepe et al., 2024)

increased body size | P-stage, with Scer\GAL4^phtm.PO

(Pan and O'Connor, 2021)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Alk^JF02668, Ptth^120F2A, Scer\GAL4^phtm.PO has increased mortality during development phenotype, enhanceable by Pvr^GD14375, Scer\GAL4^phtm.PO

(Pan and O'Connor, 2021)

Alk^JF02668, Scer\GAL4^phtm.PO has abnormal developmental rate phenotype, enhanceable by Pvr^GD14375, Scer\GAL4^phtm.PO

(Pan and O'Connor, 2021)

Alk^JF02668, Scer\GAL4^phtm.PO has increased body size | P-stage phenotype, enhanceable by Pvr^GD14375, Scer\GAL4^phtm.PO

(Pan and O'Connor, 2021)

NOT Enhanced by

Statement

Reference

Alk^JF02668, Ptth^120F2A, Scer\GAL4^phtm.PO has increased body size | P-stage phenotype, non-enhanceable by Pvr^GD14375, Scer\GAL4^phtm.PO

(Pan and O'Connor, 2021)

NOT suppressed by

Statement

Reference

Alk^JF02668, Ptth^120F2A, Scer\GAL4^phtm.PO has increased body size | P-stage phenotype, non-suppressible by Pvr^GD14375, Scer\GAL4^phtm.PO

(Pan and O'Connor, 2021)

Enhancer of

Statement

Reference

Scer\GAL4^phtm.PO, Alk^JF02668 is an enhancer of increased body size | P-stage phenotype of Ptth^120F2A, Pvr^GD14375, Scer\GAL4^phtm.PO

(Pan and O'Connor, 2021)

Alk^JF02668/Scer\GAL4^phtm.PO is an enhancer of abnormal developmental rate phenotype of Ptth^120F2A

(Pan and O'Connor, 2021)

Alk^JF02668, Scer\GAL4^phtm.PO is an enhancer of abnormal developmental rate phenotype of Pvr^GD14375, Scer\GAL4^phtm.PO

(Pan and O'Connor, 2021)

Alk^JF02668, Scer\GAL4^phtm.PO is an enhancer of increased body size | P-stage phenotype of Pvr^GD14375, Scer\GAL4^phtm.PO

(Pan and O'Connor, 2021)

Other

Statement

Reference

Alk^JF02668, Pvr^DN.UASp, Scer\GAL4^phtm.PU has abnormal eclosion rhythm phenotype

(Cavieres-Lepe et al., 2024)

Alk^JF02668, Ptth^120F2A, Scer\GAL4^phtm.PO has partially lethal phenotype

(Pan and O'Connor, 2021)

Alk^JF02668, Ptth^120F2A, Scer\GAL4^phtm.PO has increased body size | P-stage phenotype

(Pan and O'Connor, 2021)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

27518

y¹ v¹; P{TRiP.JF02668}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Alk^JF02668

Name Synonyms

Secondary FlyBase IDs

References (9)

Report Sections

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