FB2025_01 , released February 20, 2025
Allele: Dmel\Pi3K92EJF02770
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General Information
Symbol
Dmel\Pi3K92EJF02770
Species
D. melanogaster
Name
FlyBase ID
FBal0242352
Feature type
allele
Associated gene
Dmel\Pi3K92E
Associated Insertion(s)
Carried in Construct
P{TRiP.JF02770}
Also Known As
UAS-Pi3k92E-RNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
in vitro construct
(Perkins et al., 2009)
Progenitor genotype
Carried in construct
P{TRiP.JF02770}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-JF02770
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression under the control of Scer\GAL4eya.enh1+E+2 results in a small eye phenotype.

      (Pletcher et al., 2019)

      Posterior dorsocentral bristle neurons expressing Pi3K92EJF02770 under the control of Scer\GAL4pnr-MD237 show a significantly decreased terminal arbor territory and significantly fewer synapses (Syt1 puncta) on the contralateral collateral branch, as compared to controls.

      (Urwyler et al., 2019)

      Mid-third instar larvae expressing Pi3K92EJF02770 in the fat body in the fat body under the control of Scer\GAL4DcG exhibit moderately increased haemolymph glucose levels.

      Mid-third instar larvae expressing Pi3K92EJF02770 in muscle under the control of Scer\GAL4Mef2.PU exhibit moderately increased haemolymph glucose levels.

      (Ugrankar et al., 2015)

      The amplitude of the excitatory junctional current at the neuromuscular junction is significantly reduced compared to wild type in larvae expressing Pi3K92EJF02770 under the control of Scer\GAL4n-syb.PS.

      (Khuong et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Pi3K92EJF02770
      Name Synonyms
      Secondary FlyBase IDs
        References (16)